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Short-chain dehydrogenases/reductases : structure, function and motifs of hydroxysteroid dehydrogenases
(2002-11-15)
Short-chain dehydrogenases/reductases (SDR) constitute a superfamily of proteins catalysing reactions of a wide range of substrates in all life forms. During the past years, a large number of new proteins belonging to this ...
Regulation of calcium flux by activating and inhibitory receptor crosstalk in NK cells
(2019-05-27)
The birth of a new born child kicks off the immune system to be on call and to respond promptly to threats from the environment. Natural Killer cells, classified as a member of the innate lymphoid cell family, express ...
Interleukin 15 throughout murine natural killer cell biology
(2020-07-31)
Natural killer (NK) cells are innate immune cells that mount responses against virally infected, transformed and allogeneic transplanted cells. Equipped with cytolytic molecules and death receptors, NK cells mediate ...
Tartrate resistant acid phosphatase in the immune and nervous system : distribution and pathophysiological implications
(2007-11-16)
Tartrate resistant acid phosphatase (TRAP) belongs to the family of
purple acid phosphatases (PAP). It is a glycoprotein synthesized as a
monomer with low enzyme activity containing a redox active diiron centre
in the ...
Neural control of inflammation
(2021-03-31)
Pioneering research on neural control of inflammation has paved the way for new and exciting developments in the growing field of bioelectronic medicine. In the past couple of decades, pre-clinical research on the role of ...
Receptor localization and dynamics of murine natural killer cells at single cell level : using advanced fluorescence microscopy
(2017-12-21)
Natural Killer (NK) cells are immune cells and important for the defense against virally infected and malignant cells. NK cells are regulated by germline encoded activating and inhibitory receptors. Activating receptors ...
Optimizing treatment : tumor markers and sclerotherapy in head and neck lesions
(2021-05-06)
Treatment of malignant and benign lesions in the head and neck area is challenging, due to complex anatomy and function. It is thus urgent to find ways to individualize treatment, in order to reduce side-effects, but with ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
Surgery is standard treatment for early stage endometrial cancer (EC), the most common gynaecological malignancy in developed countries. Traditionally, surgery has been performed by laparotomy (LT). Comprehensive surgical ...