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On the role of NMDA receptor subunits in the acute and chronic effects of nicotine
(2005-03-18)
Nicotine is considered the main dependence-producing constituent in tobacco products. In analogy with other drugs of abuse, nicotine enhances dopamine (DA) neurotransmission within the mesocorticolimbic DA system. This ...
Studies of genetic mosaicism in rare diseases
(2022-04-01)
Mosaicism in human genetics refers to an individual harboring two or more genetic compositions, all derived from the same fertilized egg. Common signs of genetic mosaicism are asymmetric growth, skin aberrations or vascular ...
Individually tailored internet-based treatment for depression and comorbid conditions
(2018-12-21)
Background: Depression is a large societal problem. People suffering from depression are heterogeneous and have a high degree of comorbid conditions. Pharmacological treatment is widespread, but not effective for all ...
Expression and function of TRP channels in peripheral sensory neurons
(2009-05-19)
Transient receptor potential (TRP) channels comprise a family of multifunctional proteins which has since its discovery been of particular interest in sensory biology even though they are also frequently expressed in ...