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Analysis of kidney glomerular and microvascular transcriptomes
(2007-09-21)
Kidney glomeruli play a crucial role in the maintenance of body homeostasis. Many diseases attack the kidney function by primarily affecting glomeruli. However, the transcriptome profiles and the function of the glomerulus ...
Art of tumor immunity : extricating hypoxia-driven immunosuppression in the solid tumor microenvironment
(2023-09-20)
The fate of tumors, from initiation to in situ carcinoma and ultimately metastasis, is intricately tied to the balance between the immune system’s effector cytotoxic and tolerogenic immunosuppressive responses, collectively ...
Regulation of G2 phase and long-term consequences of DNA damage
(2021-04-08)
Cell proliferation requires the accurate replication of DNA and equal segregation of replicated genes, important for maintaining the integrity of newly formed cells. At the centre of this process is a series of coordinated ...