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Mechanisms influencing activation and survival of normal and malignant lymphoid cells in the testis
(2002-11-28)
Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy and the testis is the third most common site of relapse after treatment. Testicular function is regulated by pituitary hormones, but the testicular ...
Women’s experiences of fetal screening for Down’s syndrome by means of an early ultrasound examination
(2005-03-25)
The general aim of this thesis was to explore women’s reactions to and experiences of fetal screening for Down’s syndrome (DS) by means of an ultrasound examination, including measurement of fetal nuchal translucency (NT). ...
Investigation of hepatocyte signaling pathways in chronic kidney disease : clinical and experimental studies
(2016-05-25)
Chronic kidney disease (CKD) is defined as a loss of renal function from any cause and lasting for more than three months. The CKD phenotype is similar across multiple etiologies, suggesting that renal damage itself is a ...
Characteristics of cytochrome P450-catalysed drug metabolism with focus on a black Tanzanian population
(2003-11-21)
The cytochrome P450 (CYP) enzymes display interindividual and interethnic variability that may alter the disposition of substances metabolised by these enzymes. Both genetic and environmental factors such as concomitant ...
Health care on equal terms for immigrants in Sweden
(2012-08-24)
Background: There is limited knowledge about immigrant patients’ lower self-reported health (SRH) in relation to acculturation and discrimination and about immigrant patients’, interpreters’ and GPs’ experiences, reflections, ...