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Sentinel node based immunotherapy of cancer
(2007-05-25)
The tumor draining lymph node, the sentinel node, is regarded as a valuable station for staging and evaluating prognoses for patients with cancer. The object of this thesis was to investigate the immune response against ...
Genome-plasticity and adaption in Helicobacter pylori
(2004-12-31)
Helicobacter pylori is a gastric bacterial pathogen that infects an estimated half. of the human population. The infection is primarily acquired during early childhood and causes a persistent infection that is usually not ...
Impact of targeting MYC in metabolic reprogramming and differentiation of cancer
(2022-11-25)
Alterations in several metabolic pathways due to increased energy and biomass demand, as consequence of the uncontrolled proliferation of cancer cells, is known as metabolic reprogramming. Mutations in tumor suppressor ...