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Embryonic and adult cardiac stem cells : molecular, electrophysical and immunological characteristics for cardiac repair
(2011-09-27)
Background: The concept of myocardial regeneration by means of stimulating the endogenous regenerative potential in situ is an attractive approach. This offers distinct advantages to stem cell implantation where the problems ...
The zebrafish as a model to elucidate human diseases and development
(2011-08-15)
the phenotypic and molecular characterization of another of these zebrafish motility mutants, frozen (fro). I present evidence that the frot027c mutation disrupts the locus encoding the autophagy pathway component Atg10. This analysis implicates Atg10...
Increasing access to medical abortion
(2012-11-12)
been made 1180 women were randomized to medical abortion provision by a physician or nurse midwife. Both provisions were equally effective with the risk difference of 1,6% within the set margin of equivalence of 5% (p=0,027). Women randomized to nurse...
Anti-diabetic effect of gynostemma pentaphyllum tea in type 2 diabetes
(2011-10-13)
) levels and suppressing HGO levels significantly (Paper IV). The PG levels decreased from 9.8 ± 0.6 to 6.8 ± 0.4 mmol/L (p = 0.027) in GP- treated rats, whereas PG levels were not significantly decreased in the placebo rats. Glucose tolerance, assessed...
Predictive and prognostic biomarkers in oral tongue squamous cell carcinoma
(2010-11-19)
Oral tongue squamous cell carcinoma (OTSCC) is an aggressive disease frequently associated with poor prognosis due to the high risk of regional failure and mortality rates have been practically unchanged in Sweden the last ...
Organization of the spinal locomotor network in zebrafish : pattern of recruitment and origin of excitatory drive
(2012-11-21)
Locomotion is of vital importance for animals to survive in a complex environment. Locomotor movements are generated by neuronal networks that reside in the spinal cord and are composed of motoneurons and interneurons. The ...
The clinical use of genetic analyses in colorectal cancer
(2011-11-22)
Background: Colorectal cancer (CRC) is a common global disease, with a mortality rate of almost 50%. Prognosis is mainly based on the TNM classification. Surgical interventions have the potential of being curative in ...
Interventional studies on immunological balance in IBD and allergic asthma
(2010-12-16)
recruited into the bronchial mucosa and regulate allergic asthma reaction. Patients who mounted a late-phase reaction in connection to allergen challenge were designated dual responders opposite to single responders. Our finding that IL4+CD4+ cells decreased...
Genome and transcriptome studies of the protozoan parasites Trypanosoma cruzi and Giardia intestinalis
(2012-10-18)
transcriptome analysis using paired-end RNA-Seq of three distinct genotypes of Giardia intestinalis (A, B and E). Gene expression profiles recapitulated the known phylogeny of the examined genotypes, and 61 to 176 genes were differentially expressed. 49,027...
Socioeconomic disadvantage in childhood and later risk of schizophrenia and other psychoses : national register-based studies
(2010-11-19)
disadvantage (study I, IV). First and second generation immigrants had increased risks for schizophrenia and other psychoses (HRs 1.4-3.1 and 1.0-2.0 respectively), compared with the Swedish majority population. These risks decreased considerably after...