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Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
Background: The brain atrophy in individual Alzheimer's disease (AD) patients includes not only specific atrophy from AD pathology, but also atrophy induced by normal aging and cerebral vascular diseases. Although medial ...
Oral health in patients with chronic kidney disease
(2009-11-13)
Chronic kidney disease (CKD) is a complex disorder in which active intervention leads to longer survival expectancy. Oral diseases are complex disorders caused mainly by bacterial, fungal, or viral infections, where primary ...
Tissue biomarkers in prostate cancer
(2009-09-25)
Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely ...
Clinical aspects of Mycoplasma genitalium infection
(2010-01-15)
The microorganism Mycoplasma (M.) genitalium was first isolated by culture in 1980. Further attempts to culture this mycoplasma were difficult because of its slow growing nature. The development of polymerase chain reaction ...
Skin cancer in relation to tobacco use and organ transplantation
(2009-01-02)
Background: Skin cancer incidence in fair-skinned populations has increased more rapidly than any other cancer form during the past several decades. The possible impact of common exposures in the population, such as tobacco ...
Study of pruritus in psoriasis vulgaris : role of tachykinins
(2009-01-23)
Pruritus has not been considered as the most important symptom of
psoriasis. In the present thesis various methodologies have been used to
investigate this symptom in psoriasis.
The focus groups created a proper ...
Diabetes mellitus in patients with coronary artery disease : cardiovascular risk assessment and impact of available treatments
(2008-11-28)
A majority of patients with coronary artery disease have abnormal glucose
regulation and as many as 30% overt diabetes mellitus. Despite
considerable improvements in the management of cardiovascular diseases,
patients ...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Diabetes mellitus and coronary artery surgery : clinical and epidemiological studies
(2008-12-26)
Objectives: Assess early and late mortality and incidence of acute
myocardial infarction (AMI) after coronary artery bypass grafting (CABG)
in patients with and without diabetes mellitus (DM) in relation to type
of ...
Studies on syndecan-1 in mesenchymal tumors
(2010-01-08)
The syndecans are a four-member family of type I transmembrane proteoglycans. Their core proteins have a short cytoplasmic domain, a transmembrane domain and a large N-terminal extracellular domain possessing glycosaminoglycan ...