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Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
) ml/min/1.73 m2 and 33% had at least moderate renal dysfunction. Patients with lower renal function differed by being older and having more co-morbidities. They presented less often with chest pain and ST-elevation MI. After adjustments, lower renal...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
biologically active indolothiopyrans and related selenopyrans, as analogues of indolocarbazoles. The target compounds were accessed via treatment of C-2 metalated indoles with bis(phenylsulfonyl) sulfide or selenide, followed by cyclization of the intermediate...
Early function of KCC2 and Wnt genes : cytoskeletal effects in neural stem cells
(2008-09-19)
From closure of the neural tube until formation of neuronal networks,
cells undergo several crucial changes which depend on the expression of
many important molecules. GABA, the principal inhibitory neurotransmitter
in ...
The role of 5'-nucleotidases and deoxynucleoside kinases in responses to nucleoside analogues
(2010-04-30)
The efficacy of nucleoside analogues (NAs) in treating several
hematological malignancies, solid tumors and viral infections is limited
primarily by side-effects and the development of drug resistance. The
aims of the ...
The Rarebit fovea test : a new measure of visual function
(2008-04-23)
Visual acuity (VA) measurement by the use of letter charts is the most
frequently used method for testing foveal function. However, since a
decimal visual acuity of 1.0, often used as limit for normality, can be
achieved ...
In vivo functions of mammalian glutaredoxin 2
(2008-08-29)
inactive. Monomerization induced by both oxidants and reductants activated the protein. Based on these findings, we have proposed a role as redox-sensor for the cluster: under normal conditions the majority of Grx2 in the cell is present in the inactive...
Clinical aspects of Mycoplasma genitalium infection
(2010-01-15)
in both men and women. The highest clearance rate was achieved when azithromycin was given in a dose of 500 mg day 1 followed by 250 mg days 2-5. This regimen is today recognized as the treatment of choice for M. genitalium infections. The clinical...
Transcriptional regulation of healthy and diabetic pancreatic beta-cell gene expression
(2008-11-07)
Hyperglycemia, deficient insulin secretion, and insulin resistance are the characteristic pathogenetic features of type 2 diabetes (T2D), hallmarked by functional and survival defects of the insulin-producing islet beta-cell. The primary...
Regulation and function of thioredoxin reductase 1 in human tumor cells
(2009-05-22)
The thioredoxin system is a general protein disulfide reductase system
present in all organisms. Its function is to maintain an intracellular
reducing environment and upholding a defense against reactive oxygen
species ...