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European bioimaging facility survey report
(Karolinska Institutet, 2017-10-05)
This report describes the results of a survey undertaking by NatMEG (the Swedish national facility for magnetoencephalography; www.natmeg.se), performed under the auspices of Swedish Bioimaging. The three Swedish national ...
p73 : regulator of differentiation and apoptotic cell death
(2007-05-04)
Neoplasia is characterized by cells' loss of self-control due to
deregulated apoptotic and cell proliferation pathways. Anticancer
treatments aim to induce either cell cycle arrest or apoptosis, and these
effects are ...
Efficacy of artemisinin based combination therapy and effectiveness of rapid diagnostic test for management of patients with plasmodium falciparum malaria in Zanzibar
(2009-05-19)
. Some 1887 patients were enrolled between February and August 2005. Follow-up was 14 days. ACT was to be prescribed to patients diagnosed with malaria in both groups.
Results: Study I. PCR adjusted cure rates by day 42 were 188/206 (91%) for ASAQ...
Diverticular disease of the colon - risk factors and validation of diagnosis
(2024-01-08)
Positive Predictive Value for both years and all diagnoses was high, 95% (95% CI: 93-96). The Positive Predictive Value for the year 2010 was slightly higher 98% (95% CI: 95-99) than for the year 2002, 91% (95% CI: (87-94). The higher Positive Predictive...
Weight loss programmes over the internet : opportunities and limitations
(2007-11-21)
Background: Overweight and obesity is increasing in Sweden and over the
world. The societal resources to treat obesity are scarce. Eighty percent
of the population in Sweden have access to a computer and hence the
Internet. ...
Exploring statistical models for estimating remaining life years & loss in life expectancy for cancer patients
(2024-03-08)
As advancements in cancer prognosis and treatment continue for many cancer types, there is a growing interest in estimating survival over longer time periods. The assessment of the years remaining after a cancer diagnosis, ...
Inhibition in cognition : neurophysiology and connectivity of gabaergic interneurons in the prefrontal cortex
(2021-11-12)
The prefrontal cortex (PFC) is a cortical region involved in higher-order cognitive functions, it is widely connected to the rest of the neocortex and is involved in tasks that require temporal integration of information. ...
Fishing for small molecules to treat diabetes, from a beta cell perspective
(2023-10-27)
-based cell cycle indicator (LUCCI), identified a small molecule called HG-9-91-01, an inhibitor of salt-inducible kinases (SIKs), as a mitogen of mouse and human β cells. Mechanistic studies found HG-9-91-01 induced a transient upregulation of ATF6-dependent...
Engineering cell communication from nanoscale to tissue levels towards therapeutic applications
(2024-02-22)
Cell communication which is vital for the proper function, development, and survival of multicellular organisms is often disrupted in diseases. This thesis aims to enhance our understanding of cell communication by employing ...
Clinical characteristics and treatment outcomes in body dysmorphic disorder
(2024-02-01)
regarding the presence or absence of a diagnosis was high for both disorders (95.2% for hypochondriasis and 92.6% for dysmorphophobia), and 80% of the hypochondriasis files and 91% of the dysmorphophobia files were considered ‘true positive’ cases...