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Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Studies on arachidonic acid metabolism in normal and malignant hematopoietic cells
(2010-01-15)
involved in arachidonic acid metabolism and the capacity to generate leukotriene (LT) B4 via the 5-lipoxygenase pathway in blood tumor cells from patients with precursor B-ALL (acute lymphoblastic leukemia) and AML (acute myeloid leukemia). In addition...
The role of CYP3A4/5 in alprazolam metabolism
(2010-05-14)
Cytochrome P450 3A (CYP3A) enzyme family is involved in the metabolism of about 50 % of all drugs in clinical use. Among CYP3A, CYP3A4 and CYP3A5 are the major enzymes in adults; however CYP3A5 is polymorphic and primarily expressed in black...
Short and long term effects of bacterial gastrointestinal infection
(2008-05-09)
The objectives of this thesis were to increase our understanding of the
mortality and complications associated with bacterial gastrointestinal
infections, with focus on Salmonella and Campylobacter enteritis. The
effect ...
Traffic noise and cardiovascular disease
(2010-04-30)
Traffic noise is an increasing problem in urban areas worldwide, but health effects in relation to traffic noise exposure are not well understood. Several studies show that noise may give rise to acute stress reactions, ...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
occurrence of psychoactive plant use in Sweden. Studies were done in attempt to elucidate the metabolic pattern of α- and b-asarone in humans. Cis(b)-2,4,5-trimethoxycinnamic acid was regarded to be the most abundant metabolite, evidence of a hydroxylated...
Studies of the device perfect capsule in an animal model to reduce lens epithelial cell proliferation
(2008-09-12)
The sealed-capsule irrigation device, the Perfect Capsule, is a surgical
device designed to target lens epithelial cells (LECs) during cataract
surgery and prevent posterior capsule opacification (PCO). This is
especially ...
Studies on cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in lymphomas
(2008-08-22)
Classical Hodgkin lymphoma (cHL) is a malignant disorder with striking
inflammatory features. Since cysteinyl leukotrienes (cysLTs) are potent
inflammatory mediators it was of interest to study their potential role
in ...
Transcription factor control in neuronal maintenance and survival
(2010-04-16)
is evident in Parkinson s disease, the most frequent neurodegenerative movement disorder. In addition Nurr1 is expressed in a number of other CNS areas. In the hippocampus, Nurr1 is co-expressed with its homologues Nur77 and Nor1, collectively named for NR4A...
Manipulating neural stem cells
(2010-03-17)
one factor, Oct4. In manuscript IV Oct4 expression is chemically induced. Endogenous expression of the pluripotency factors Nanog and Rex1 were measured to investigate whether Oct4-inducing conditions could lead to a reprogrammed state....