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Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
-cell interactions of committed ectodermal cells. We also showed that expression of the Wnt PCP signalling gene Vangl2 (Van gogh-like 2) was increased. Wnt7a´s influence on neuronal differentiation was studied by investigation of β-tubulin III expression, a marker...
Prevention and intervention therapies in auditory trauma
(2009-01-16)
Hearing impairment is one of the most common health conditions in
developed countries. It is estimated that approximately 70 million people
worldwide are deaf. For patients with a severe to profound hearing loss a
cochlear ...
Alternative splicing of interleukin-7
(2009-04-03)
to function as either agonists or as antagonists of the wildtype cytokine. Interleukin-7 (IL-7) plays a non-redundant role in early stages of normal B and T-cell development; IL-7-receptor signaling is required for the maintenance of T-cell homeostasis...
CD8alpha/alpha+ T-cells and immune memory
(2009-04-29)
TB vaccination and after Mtb infection was further analyzed in Paper IV. CD8αα+ T-cells underwent similar phenotypical changes as observed in the CD4+ and CD8αβ+ T-cell compartments, in vaccinated but not in non-vaccinated animals: loss of IL-7Rα...
Storage and transfusion of platelets : in vitro and in vivo studies in healthy volunteers and in allogeneic hemapoetic progenitor cell transplant recipents
(2009-03-13)
Early studies in the 1960´s showed that platelet (PLT) transfusions
significantly reduced the incidence of fatal hemorrhages. Together with
the advances in the hematology and transplantation field, easily
accessible ...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
The aim of this thesis is to evaluate the influence of renal dysfunction on the presentation for myocardial infarction (MI), its treatment and outcome. Patients between 2003 and 2006 were selected from the nationwide Swedish ...
Intramuscular or periosteal acupuncture for patients with chronic musculoskeletal pain in the neck and low back : effects on pain, physical and psychological functioning
(2008-10-23)
Background: Periosteal acupuncture has shown promising results in the
clinic. No studies of effects in patients with chronic pain in the neck
and low back are today available.
Aims: The main purpose was to compare ...
Evaluations of measurement techniques in functional dyspepsia : electrogastrography, satiety drinking test and 14C-urea breath test
(2010-08-20)
The overall aim of this thesis was to evaluate the clinical usefulness of certain measurement techniques that may be helpful in the understanding of functional dyspepsia (FD). Electrogastrography (EGG) parameters were ...
Determinants of long term course in bipolar disorder
(2010-05-14)
Introduction: Bipolar disorder (BP) is a common and severe psychiatric
illness with a high variability. An early treatment is often crucial for
a good prognosis, but it is difficult for clinicians to define high ...