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Genome wide analysis of the Ssn6-Tup11/Tup12 co-repressor complex in the fission yeast Schizosaccharomyces pombe
(2007-02-15)
In this study, we have investigated the fission yeast Ssn6-Tup11 /Tup 12
transcriptional corepressor which is involved in regulation of many genes
important for a wide variety of processes. In contrast to the well
characterised ...
Physical activity in the severely obese : studies on measurement and promotion
(2007-03-26)
Background: The amount and quality of evidence on how to effectively
promote physical activity (PA) is low compared to what is known about the
health effects of regular PA, especially in obese individuals.
Aim : ...
Strategies to increase effectiveness of growth factor receptors-targeted therapy in glioblastoma
(2007-11-14)
Gliomas are the most common glial neoplasms, accounting for nearly 70% of
all primary brain tumours. The progression of low-grade gliomas into more
aggressive tumours is supported by the abnormal function of several
prot ...
Oral health among a group of homeless individuals from dental professional's and patient's perspective
(2007-02-09)
The homeless are a vulnerable group in society. They are frail, in poor
general health and tend to have difficulty expressing expectations and
needs. While poor oral health is clearly an added burden for people who
struggle ...
Psychosocial work conditions and musculoskeletal complaint : the role of affective stress response as a mediator of the effect of psychosocial risk factors on musculoskeletal complaints
(2007-11-22)
The hypothesis tested in these two studies was that unfavourable
psychosocial work conditions are expected to increase the risk of
musculoskeletal complaints (MSC), and that this effect is at least partly
mediated by ...
Analysis of kidney glomerular and microvascular transcriptomes
(2007-09-21)
Kidney glomeruli play a crucial role in the maintenance of body homeostasis. Many diseases attack the kidney function by primarily affecting glomeruli. However, the transcriptome profiles and the function of the glomerulus ...
Microfluidic electrocapture in proteomic sample preparation for mass spectrometry
(2007-10-19)
Proteomics is a technology-driven discipline and very labor-intensive.
Over the last couple of years, methods with microfluidic systems have
been used to simplify analytical procedures via integration of laboratory
processes ...
Toxicological studies of opiate-related death
(2007-04-25)
This thesis comprises studies on opiate overdose death, and focuses on
evaluation of toxicological characteristics including the possible
influence of abstinence and polydrug use for the fatal outcome.
In order to ...
Aspects on chronic stress and glucose metabolism in women with recurrent vulvovaginal candidiasis and in women with localized provoked vulvodynia
(2007-04-06)
cortisol was registered more often in women with RVVC (p<0.002). Mean levels of salivary cortisol were lower the first 45 minutes after awakening in women with RVVC, compared with controls. Blunted morning rise cortisol was registered more often in women...
Esophageal cancer surgery : factors influencing survival
(2007-01-19)
The principal aim of this thesis was to address factors that may affect
survival after esophageal cancer surgery. Surgical resection remains the
only established potentially curative treatment for patients with
resectable ...