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Staphylococcal cell wall associated proteins : characteristics and host interactions
(2005-11-11)
Staphylococcus aureus and Staphylococcus epidermidis are members of the same family and share several features. S. aureus causes many diseases ranging from mild skin infections to deep tissue infections and septic shock. ...
In vitro and postmortem studies of the brain opioid system : association to opiate dependence
(2006-08-25)
detected after cellular treatment with DAMGO (3 h). Annexin V, an apoptosis-induced gene and RGS4 were prominently up-regulated in this cell line.
Cultured rat adult hippocampal progenitors (AHPs) were shown to release beta-endorphin and express MOR...
Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis
(2005-05-17)
The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates ...
Catalytic mechanisms and evolution of leukotriene A4 hydrolyse
(2006-11-10)
of chemical mediators, which by different means control, maintain and resolve the process. One group of such mediators is the leukotrienes, among which LTB4 is found. LTB4 has several immunomodulating properties and mainly acts by recruiting leukocytes...
Health economics of osteoporosis
(2006-05-02)
Health economics is concerned about how the scarce resources should most efficiently be allocated to maximise the health outcomes. Health economic evaluation is a method for assessing costs and benefits of alternative ...
Modeling individual behavioral changes : the case of tobacco uptake in a cohort of school children
(2005-08-25)
The aim of this thesis was to elucidate preventable determinants of smoking and smokeless tobacco use in adolescence in the frame of a longitudinal study (BROMS cohort). The study population encompasses 3019 children ...
Humeral shaft fractures : epidemiology outcome
(2007-10-26)
Humeral shaft fractures account for 1-3% of all fractures and
approximately 20% of all humeral fractures. Non-operative treatment with
functional bracing has been regarded as the golden standard for treatment
of closed ...
Heart failure : aspects on treatment and prognosis
(2006-05-02)
The aim of this thesis was to describe aspects on treatment and prognosis in heart failure. In paper I, we studied two hundred and seventy-nine hospitalised heart failure patients, and related clinical and demograhic data ...
Aspects of inflammation in chronic obstructive pulmonary disease : a clinical study
(2006-11-03)
Development of chronic obstructive pulmonary disease (COPD) involves an amplified inflammatory response to tobacco smoke that results in a limitation of airflow. At present, the mechanisms underlying these inflammatory ...
Long-term neurodevelopmental outcome after moderate neonatal encephalopathy and after post-term birth : two population-based studies
(2006-03-17)
Long-term neurodevelopmental outcome in two population-based groups of children with different perinatal events was studied: A) Children born at term with moderate neonatal encephalopathy (NE) and B) children born post-term ...