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Psychosocial risk factors in women with coronary heart disease : stress, social support and a behavioral intervention
(2005-09-16)
to survey psychosocial and physiological risk factors for CHD in women. Participants were 292 women <65 years (mean age 55±8 yrs) recruited while hospitalized, for acute myocardial infarction (AMI) or unstable angina pectoris from all hospitals in Stockholm...
Clinical, immunological and olfactory aspects of sinusitis and nasal polyposis : with special reference to patients with cystic fibrosis
(2004-11-26)
The otorhinolaryngological approach to the problem concerning
rhinosinusitis and nasal polyposis in the recessive genetic disorder of
cystic fibrosis (CF) has been developed based on data from international
studies. ...
Structure determination, thermal stability and catalytic mechanism of hyperthermostable isocitrate dehydrogenases
(2006-05-02)
IDH was most thermostable, with an apparent melting temperature of 109.9 degrees C, whereas that of TmIDH, AfIDH and PfIDH was 98.3 degrees C, 98.5 degrees C and 103.7 degrees C, respectively. The crystal structures of the apo-forms of ApIDH, TmIDH and Af...
Posterior capsule opacification and postoperative endophthalmitis following cataract surgery : predictive and protective factors
(2005-04-01)
Modem cataract surgery with implantation of an intraocular lens (IOL) is an increasingly safe and successful procedure, though complications still occur. This thesis addresses the most common complication, posterior capsule ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A primary focus of this thesis...
Regulation of NK cell activity : studies of DAP12-associated receptors in immune synapse formation and in responses to cytomegalovirus infection
(2006-10-27)
Natural killer (NK) cell effector functions are important for innate resistance against tumor cells and viral infections. NK cells display a broad range of inhibitory and activating receptors on the cell surface, which ...
The family triad : the interaction between the child, its mother, and father from birth to the age of 4 years old
(2006-10-06)
The aim of this thesis was to describe how early triadic interaction between the newborn child and its mother and father begins, develops, and matures over the child's first 4 years of life. Systemic family theory and ...
Calcium dynamics and vesicle-release proteins in a prion-infected neuronal cell line
(2005-03-25)
The prion particle, PrPSc, is an infectious, misfolded form of the cellular prion protein, PrPC that is expressed at high levels in the central nervous system. Prions cause neurodegenerative diseases with clinical signs ...
Antiplasmin the main plasmin inhibitor in blood plasma : studies on structure-function relationships
(2005-04-06)
Antiplasmin is an important regulator of the fibrinolytic system. It
inactivates plasmin very rapidly. The reaction between plasmin and
antiplasmin occurs in several steps: first a lysine-binding site in
plasmin interacts ...
Apoptosis in chronic inflammation, with specific reference to airway disease
(2006-09-08)
Mechanisms governing the normal resolution processes of inflammation in the lung are poorly understood, yet their elucidation may lead to a greater understanding of the pathogenesis of several pulmonary inflammatory ...