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Characterisation of psoriasis lesions by protein expression profiling
(2006-05-26)
Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic ...
Endometrial, embryonic and ovarian aspects of human implantation
(2006-05-11)
The general aim of the studies was to add more understanding to the mechanism of human embryo implantation, which will allow us to improve pregnancy rates in assisted reproduction.
The simultaneous positive spatial ...
Targeting insulin-like growth factor-1 receptor in cancer
(2004-09-24)
Cancer is a multi-step process where the accumulation of several genetic and epigenetic alterations drives the transformation of a normal cell to a malignant cell, skipping the normal control of defense, repair and apoptosis. ...
Magnetic resonance imaging of rectum : diagnostic and therapy related aspects
(2006-03-31)
Papers I-II: The purpose of paper 1 was to assess the size and configuration of the perirectal fatty tissues (PF) using magnetic resonance imaging (MRI). In 25 subjects the volume and cross-sectional parameters based on ...
Tobacco smoking and periodontal health in a Saudi Arabian population
(2005-09-23)
disease was 5.1-fold and 3.8-fold increased in water pipe and cigarette smokers, respectively, compared to non-smokers (p < 0.01). The relative risk associated with heavy smoking was about 8-fold elevated in water pipe smokers and 5-fold elevated...
Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma
(2006-10-27)
The hypothalamic pituitary adrenal axis (HPA axis) regulates nearly all neuroendocrine responses of the body. An active HPA axis is crucial to maintaining homeostasis. An altered reactivity of the HPA axis can affect several ...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and ...
Coronary artery bypass surgery without extracorporeal circulation
(2006-03-10)
Introduction: Coronary artery bypass surgery with extracorporeal circulation is associated with a systemic inflammatory response syndrome that contributes to morbidity and mortality. Aortic cross clamping and cardioplegic ...
Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
Haematological malignancies constitute approximately 7% of all cancer cases in Sweden, and leukaemia is in fact the most common malignancy among children. The few established risk factors, such as ionising radiation and ...
Processing, stability and interactions of lung surfactant protein C
(2005-11-23)
Mature SP-C is a 4.2 kDa transmembrane protein which is uniquely expressed in the alveolar type II cell. Human SP-C is generated via multistep proteolytic cleavage of both the C-terminal and Nterminal regions of proSP-C. ...