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Molecular studies of Neisseria : host cell interactions
(2004-08-11)
), a cofactor for serine proteinase factor 1, preventing the assembly of C3-convertase. We found that the pilusassociated protein PilC of N. gonorrhoeae interacted with C4BP which may contribute to serum resistance by allowing the bacteria to escape...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Infant feeding and allergy in children
(2005-11-04)
and 4 years to collect information on exposures and health outcomes. The response rate at 4 years was 91%. Among these children a clinical investigation was performed in 73%, which included peak flow measurement and blood sampling for analysis...
Analysis and manipulation of autoreactive and tumor-specific T cell responses
(2004-11-29)
-derived antigen, in the pancreatic lymph nodes (PLN). Activated T cells proliferate at this site and subsequently leave the PLN and infiltrate the pancreas. Lymphocytes first appear in the pancreas at 3 weeks of age and diabetes occurs around 12 weeks of age...
Children's diarrhea in Hanoi, Vietnam : importance of enteric pathogens
(2005-02-18)
Diarrhea is one of the leading causes of illnesses and death among
children in developing countries, where an estimated 1.3 billion episodes
and 4 to 10 million deaths occur each year in children less than 5 years
of ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and ...
Orthology and protein domain architecture evolution
(2006-05-22)
A major factor behind protein evolution is the ability of proteins to evolve new domain architectures that encode new functions. Protein domains are widely considered to constitute the "atoms" of protein chains, acting as ...
On neck load among helicopter pilots : effects of head worn equipment, whole body vibration and neck position
(2005-09-13)
rotation, 2-3 % of neck flexion, and 1.5-2.5 % of trunk inclination. The use of NVG increased muscle activity in upper neck by 0.5-1.5 % and in lower neck by about 0.5 %. Results with added counterweight were about the same as with NVG. Muscle activity...
Patient-orientated aspects of the postoperative course after hernia surgery
(2006-09-01)
on the discordance between the patient's and the surgeon's perception of complications. Some 206 patients having surgery for inguinal hernia were invited to a follow-up 3-6 weeks after the operation. The patient was asked to fill in a questionnaire with 12 questions...
Matrix metalloproteases and cell motility in malignant mesothelioma
(2004-10-29)
in malignant mesothelioma cells. All investigated mesothelioma cell lines expressed mRNA for MMP-1, MMP-2, MMP-3, MMP-9 and 6/8 cell lines expressed MMP-7, 3/8 cell lines expressed MMP-10. MMP-11 was not detected in any of mesothelioma cell lines tested. MMP-2...