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The influence of psychosocial stress, socioeconomic differences and coffee consumption in the etiology of type 2 diabetes
(2004-12-24)
Type 2 diabetes is a chronic disease of multiple etiology and with increased prevalence during the past two decades. We investigated the influence of psychosocial stress in association with type 2 diabetes and looked further into possible...
Standardization and application of quantitative PCR methods in patients with hematological malignancies
(2004-10-29)
(ABL, GUS, B2M). We applied RQ-PCR to investigate the differences over time in the stabilities of FG and CG transcripts, which may result in over- or under-estimation of MRD levels. The mean stability of most FG transcripts seemed to be comparable...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
In a murine model of contact allergy, 24 h after challenge with antigen, increased axonal growth using an antibody to growth-associated protein-43 (GAP-43) was seen in the epidermis and dermis of eczematous skin. Protein ...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
locomotion decreases the burst frequency and produces long-lasting oscillations of the intracellular Ca2+ concentration. These oscillations are mediated through PLC and Ca2+ release from internal stores. Furthermore, they are also dependent on Ca2+ influx...
PET studies of the serotonin transporter in the human brain
(2006-10-27)
of neurotransmission systems in the human brain in vivo. Though suitable radioligands are available for the serotonin 5-HT1A and 5HT2A receptor subtypes, imaging studies of the 5HT transporter (5-HTT), a key target for drug treatment of mood and anxiety disorders, has...
Mental and physical health among first-generation and second-generation immigrants in Sweden
(2006-09-11)
-generation immigrants and whether having one parent born in Sweden has a protective effect on this risk (study 2). To examine whether the increased risk of being hospitalized for alcohol and drug abuse among certain immigrant groups is present among second...
Airway responses to NO2 and allergen in asthmatics
(2005-04-08)
to 500 µg/m3 N02 or purified air for 30 minutes, followed four hours later by an allergen inhalation challenge. Bronchoscopy was performed 19 hours after the allergen challenge. This single 1/2-hour exposure to N02 followed by allergen gave an increase...
Interactions between neural retina, retinal epithelium and choroid
(2006-05-25)
The retinal pigment epithelium (RPE) is a non-replicating monolayer that plays a key role nursing the photoreceptors of the neural retina, regulating fluid movement within the subretinal space, maintaining a basal laminar ...
Renal cell death in urinary tract infections : role of E. coli toxins
(2005-01-28)
cell death in a dose- and time-dependent manner. The expression of Fas receptors and the phosphorylated extracellular signal-regulated kinase 1/2 (ERK1/2) were significantly upregulated by E.coli soluble toxins. Cell death could be completely inhibited...