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Cellular immune responses against human parvovirus B19 infection
(2006-04-14)
The role of cellular immune responses in the control of Parvovirus B19 (B19) infection has not previously been investigated. B19 does not normally cause severe clinical problems but complications may arise in immunosuppressed ...
Perioperative nutrition and insulin resistance
(2006-01-27)
development of postoperative insulin resistance. Insulin sensitivity, glucose kinetics (6,62H2-D-glucose) and substrate utilisation were studied before surgery and on the third postoperative day in 13 patients undergoing colorectal resections. Patients were...
The pathophysiology of respiratory chain dysfunction
(2005-02-18)
Mutations of mitochondrial DNA cause a variety of clinical syndromes. It is unclear whether impaired oxidative phosphorylation on its own is the main cause of pathology or whether other factors such as secondary metabolic ...
Regulation of carbohydrate metabolism in skeletal muscle during and after contraction
(2006-11-03)
It is well known that exercise increases glucose transport into skeletal muscles. The regulation of this transport, however, is poorly understood. An increased understanding of the mechanisms underlying glucose transport ...
Prevention of complications in pediatric cataract surgery
(2004-11-26)
This thesis was performed to find ways to lessen the complications to pediatric cataract surgery, which is an increasingly safe procedure, also in infants. However, there are some complications to the surgery, which threatens ...
In vitro and in vivo studies on biodegradable matrices for autotransplantation
(2006-04-07)
Tissue engineering (TE), one of the most rapidly growing fields of life science, is an interdisciplinary area in which technical, biological and medical expertise co-fertilize on another with the ultimate aim of restoring, ...
Structural studies of lumazine synthases : thermostability, catalytic mechanism and molecular assembly
(2005-12-27)
B. subtilis, A. aeolicus and a designed mutant LS from A. aeolicus (structure determined by cryo-EM in manuscript IV) were studied using small angle x-ray scattering (SAXS) and cryo-EM. The results indicate that multiple assembly states are a general...
Health related lifestyle habits of Swedish schoolchildren : studies on knowledge, conception and behaviour
(2006-05-26)
Aim: The overall aim of this thesis was to evaluate the effects of the health education programme "An adventure with Pelle Pump". Further the aim was to provide knowledge of importance for the development of future programmes ...
Life situation after stroke : the spouses' perspective
(2005-09-23)
In Sweden approximately 30,000 people suffer from stroke every year, of which some 20,000 for the first time. The disease is one of the most disabling chronic diseases in the adult population, with severe consequences for ...
Genomics and bioinformatics approaches to functional gene annotation
(2006-02-02)
Biomedical research has been undergoing a quasi-revolution with the dawn of the genomics era. The flood of sequence data from the various genome projects, the task of cataloging the entire coding portion of a genome instead ...