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Adult neurogenesis : from stem cell to functional neuron
(2005-05-06)
The adult mammalian central nervous system harbors a population of neural
stem cells with the ability to generate neurons, astrocytes and
oligodendrocytes. These pluripotent cells can be enriched in vitro, and
by directing ...
Pleurodesis in chronic effusions : studies on inflammatory mediators, respiratory function, predictability of treatment outcome, drug efficiency and survival after treatment
(2004-09-17)
Metastatic or primary (mesothelioma) malignancy of the pleura often
generates major pleura] effusion, giving respiratory distress and low
quality of life to the patients. Evacuation of fluid by thoracocentesis
gives ...
Studies of high mobility group chromosomal protein 1 as a pro-inflammatory cytokine
(2005-05-27)
High mobility group box chromosomal protein 1 (HMGB 1) is a nuclear protein recently recognised as a pro-inflammatory cytokine with implications both in acute and in chronic inflammation. HMGB1 has been reported to act as ...
Mechanisms of resistance to ciprofloxacin in Neisseria gonorrhoeae
(2006-04-07)
A few years ago, most strains of Neisseria gonorrhoeae were susceptible to ciprofloxacin, but after introduction as a first line therapy, resistant strains emerged. Ciprofloxacin inhibit two enzymes necessary for DNA ...
Evaluation of the DIAGNOdent method for detection and quantification of carious lesions : in vitro and in vivo studies
(2005-03-08)
The sites most susceptible to dental caries are the occlusal surfaces and
the margins of existing restorations. These are also the sites at which
lesion detection by conventional methods is most unsatisfactory. There ...
Platelets and eosinophils in lung tissue remodelling
(2006-08-25)
Tissue injury and inflammation followed by effective repair restores normal function, but defective repair with associated tissue remodelling and fibrosis can lead to loss of organ function. Thus, interactions between ...
Clinical and economic features of categories of patients in defined populations
(2005-11-18)
This thesis addresses the use of information from health care registers on an individual level, making it possible to elucidate the morbidity and comorbidity patterns in defined populations, and to allocate resources in ...
Inflammation and neurodegeneration in mouse nervous system : experimental application
(2006-01-26)
Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated inflammatory autoimmune disease of peripheral nervous system (PNS) and shares many of clinical, immunological, electrophysiological and morphological ...
The road from atherosclerosis to myocardial infarction : studies in an experimental model
(2005-09-30)
Atherosclerosis is a slow progressing disease with continuous lipid deposition and inflammation in the arterial wall. Stenotic arteries may cause angina pectoris but it is the sudden formation of an occluding thrombosis ...
Influence of the microflora on gastrointestinal nitric oxide generation : studies in newborn infants and germ-free animals
(2006-05-11)
Interactions between intestinal bacteria and the host play an important role in physiological regulation of gut function and in development of various diseases. Nitric oxide (NO) exhibits a variety of biological actions ...