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Epstein-Barr virus (EBV) latent membrane protein (LMP) 2A
(2005-11-11)
Epstein-Barr virus (EBV) is a ubiquitous human herpes virus which infects more than 90% of individuals in the population and is causally implicated in lymphoid and epithelial malignancies. Virus invades oropharyngeal mucosa ...
Exercise and angiogenic growth factors in human skeletal muscle
(2005-05-20)
Long-term electrical stimulation and endurance exercise increase the amount of capillaries in skeletal muscle. VEGF-A is a well-characterized stimulatory angiogenic growth factor and has shown to play an important role in ...
High resolution genomic tools for the discovery of protein function in mammalian cells
(2006-05-19)
The work described in this thesis emphasizes the development of cell-based strategies with increased throughput design that enable rapid biological discovery through direct investigation of protein function. Each of the ...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
This thesis is mainly focussed oil the synthesis of marine indole alkaloids and related systems, many of which display interesting biological activities.
In the first part of this thesis we could establish and confirm ...
The fibrinolytic enzyme system : new markers of potential interest in cardiovascular disease
(2005-12-30)
Impaired fibrinolytic function, mainly due to elevated plasma levels of PAI-1, is a common finding in patients with coronary heart disease. Determination or evaluation of the plasma PAI-1 concentrations are complicated, ...
Diagnostic tests for adiposity and metabolic risk factors in adolescence : results from the Stockholm weight development study (SWEDES)
(2005-03-25)
Background: Despite growing concern about the development of pediatric
obesity, there is still controversy about its classification.
International classification systems have been proposed and national
systems are in ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and ...
Assessment of anti-diabetic effect of Vietnamese herbal drugs
(2005-11-18)
stimulated insulin release at 3.3 and 16.7 mM glucose from isolated rat pancreatic islets of both W and GK rats. Interestingly, B- cell sensitivity to phanoside is higher at 16.7 mM than at 3.3 mM glucose, since significant insulin responses were observed...
Long-term neurodevelopmental outcome after moderate neonatal encephalopathy and after post-term birth : two population-based studies
(2006-03-17)
Long-term neurodevelopmental outcome in two population-based groups of children with different perinatal events was studied: A) Children born at term with moderate neonatal encephalopathy (NE) and B) children born post-term ...
Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma
(2006-10-27)
The hypothalamic pituitary adrenal axis (HPA axis) regulates nearly all neuroendocrine responses of the body. An active HPA axis is crucial to maintaining homeostasis. An altered reactivity of the HPA axis can affect several ...