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Expression of cathelicidin antimicrobial peptides in man and rat
(2004-11-26)
Endogenous antimicrobial peptides are effectors of innate immunity. They kill microorganisms by disrupting their cell membranes, but are also believed to have signaling functions in the immune system. They are present in ...
Host responses and bacterial virulence factors in Neisseria infections
(2004-08-27)
Neisseria meningitidis and Neisseria gonorrhoeae are human specific pathogens. N. meningitidis is a major cause of meningitis and sepsis, whilst N. gonorrhoeae causes many millions of cases of gonorrhea in the world every ...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Serodiagnosis and seroprevalence of Helicobacter pylori infection in Vietnam
(2006-10-19)
disease (PUD), gastric biopsies and serum samples were obtained from 296 PUD patients (age 18-88 years). H. pylori status was confirmed by culture and/or serology at inclusion, after treatment and after 12 (+/-2) months of follow-up. Serum samples from 91...
Studies on the mechanism of regulation of bile acid synthesis in humans with some aspects on genetic factors
(2005-10-28)
In the present investigation we studied human bile acid synthesis and its regulation both in vivo and in vitro and also evaluated a possible influence of polymorphisms in the CYP7A1 and CYP8B1 genes on bile acid synthesis ...
Anxiety, exhaustion and depression in relation to periodontal diseases
(2006-03-10)
level in GCF was increased, whereas the patients in Study IV surprisingly showed lower cortisol values in GCF than the controls. The level of cortisol in saliva was similar in both groups. Neither did the levels of matrix metalloproteinases-8, -9 (MMP-8...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Off-label drug treatment and related problems in children : a register-based investigation
(2006-04-21)
Introduction: There is a lack of pediatric documentation concerning efficacy and safety of many drugs, which may contribute to off-label drug treatment and increase the risk for adverse drug reactions (ADRs).
Aims: ...
Heart failure : aspects on treatment and prognosis
(2006-05-02)
The aim of this thesis was to describe aspects on treatment and prognosis in heart failure. In paper I, we studied two hundred and seventy-nine hospitalised heart failure patients, and related clinical and demograhic data ...
Epstein-Barr virus nuclear antigen 1, Oct and Groucho/TLE in control of promoter regulation
(2005-11-04)
The human herpes virus Epstein-Barr virus (EBV) is carried by
approximately 95% of the adult population. It can form a lifelong latent
infection in the B-cells by avoiding our immune system. A latent EBV
infection is ...