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The epidemiology of low back pain in the general population and after motor vehicle collisions : population-based investigations
(2004-11-23)
the
incidence and course of LBP episodes in the general adult population.
Papers I and IV are based on the same study population. A random sample
of 2,055 Saskatchewan adults received a health survey and 1,133 (55.1%)
returned completed questionnaires...
PTEN and Akt signalling in Alzheimer’s disease
(2005-11-18)
together with TNFalpha and to a lesser extent HNE. TNFalpha together with PTEN inhibition increased phosphorylation on Ser473Akt and Ser9GSK3beta that was paralleled by an increased number of viable and decreased number of early apoptotic neurons...
Insulin signaling and glucose transport in insulin resistant human skeletal muscle
(2005-08-19)
Insulin resistance in skeletal muscle is a hallmark feature of Type 2 diabetes mellitus. The overall aim of this thesis was to investigate downstream intermediates in the insulin signaling pathway in an attempt to characterize the molecular...
Hairdressers : hand eczema, hair dyes and hand protection
(2006-10-06)
for assessment of dermal exposure to permanent hair dyes on hairdressers' hands was developed and validated. The validated hand rinse method was used during hair dyeing in hairdressing salons for assessment of the exposure to p-phenylenediamine (PPD), toluene-2...
Kinetics of HIV-1 drug resistance mutations in vivo
(2006-03-10)
Antiretroviral therapy (ARV) exert a selective pressure on HIV-1 and may select viral drug resistant strains which have competitive advantage in the presence of the drug. Knowledge about the appearance and disappearance ...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
In a murine model of contact allergy, 24 h after challenge with antigen, increased axonal growth using an antibody to growth-associated protein-43 (GAP-43) was seen in the epidermis and dermis of eczematous skin. Protein ...
Gene expression in human skeletal muscle : effects of activity, fibre type and inheritance for diabetes
(2006-04-07)
One fundamental underlying risk factor for the development of non-insulin dependent (type 2) diabetes mellitus is insulin resistance, which 80-90% of all type 2 diabetic patients suffer from. Risk factors for insulin resistance are for example...
The study of sensory cilia development in Caenorhabditis elegans
(2008-01-04)
Cilia and flagella are widespread eukaryotic subcellular components
that are conserved from green algae to mammals. In different organisms
they function in cell motility, movement of extracellular fluids and
sensory ...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
revealed a right - left hand side symmetry. Cigarette smoking was significantly associated with the prevalence and severity of vertical bone defects (Studies II and III). The relative risk associated with current smoking was 2 to 3-fold increased...
Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy
(2005-01-14)
oral antidiabetic treatments, platelet hyperreactivity (increased ADP-induced P-selectin expression) was observed after a carbohydrate-rich meal in type 2 diabetes patients. Premeal treatment with repaglinide or glibenclamide reduced postmeal...