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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Modeling individual behavioral changes : the case of tobacco uptake in a cohort of school children
(2005-08-25)
The aim of this thesis was to elucidate preventable determinants of smoking and smokeless tobacco use in adolescence in the frame of a longitudinal study (BROMS cohort). The study population encompasses 3019 children ...
Kinetics of HIV-1 drug resistance mutations in vivo
(2006-03-10)
Antiretroviral therapy (ARV) exert a selective pressure on HIV-1 and may select viral drug resistant strains which have competitive advantage in the presence of the drug. Knowledge about the appearance and disappearance ...
Unstimulated human whole saliva flow rate in relation to hyposalivation and dental caries
(2005-04-08)
Introduction: Salivary secretion is influenced by a large number of factors, including the circadian rhythm, making the detection of reduced salivary flow (hyposalivation) difficult. This is important since severely reduced ...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. The synthesis of barettin and 8,9dihydrobarettin was performed in this work, involving a highly functionalised arginine derivative. This arginine derivative was used in a peptide...
Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
model. We found no association between magnetic field exposure and childhood leukaemia overall. However, elevated risk estimates were found in subgroup analyses of acute lymphoblastic leukaemia in the 5-9 year age group. Random variation is a likely...
Malaria, B lymphocytes and Epstein-Barr virus : emerging concepts on Burkitt's lymphoma pathogenesis
(2005-08-12)
in the frequency and levels of and-BZLF1 antibodies, indicative of viral reactivation. In the M+ group, the positive plasma samples clustered in a children age group of 7-9 years, the peak-age incidence of eBL. The clearance of circulating EBV after malaria...
Learning to be a physiotherapist
(2006-05-12)
Few studies have explored student experience of learning in physiotherapy and none has explored student experience throughout an education programme from a student perspective. The traditional role of physiotherapists as ...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular ...
Physical fitness and overweight in Swedish youths
(2005-03-22)
The aim of the present thesis was to describe the level of physical fitness and prevalence of overweight and obesity in Swedish youths, and their trends over 14 years. Additionally, the relation between fitness and overweight ...