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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
An epidemiological study og drug-induced acute pancreatitis utilizing a Swedish case-control network
(2006-01-06)
.2-4.8), for proton pump inhibitors 2.1 (1.2-3.4), for non-steroidal anti-inflammatory drugs derived from acetic acid 2.3 (1.3-4.0) and for antibacterial agents designed for systemic use 1.9 (1.1-3.2). Inflammatory bowel disease exhibited an OR of 3.4 (1.5-7.9), while...
Idiopathic thrombocytopenic purpura in childhood : clinical features, diagnostics and treatment
(2004-10-29)
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder
characterized by thrombocytopenia, i.e. platelet count (pl.c.)
<150x109/L, due to antibody binding to platelet antigen(s) causing their
rapid destruction ...
Application of nuclear medicine methods in patients with breast cancer
(2005-04-29)
While physical examination, mammography and aspiration cytology or core biopsy form the basis in the diagnosis of breast cancer, additional examinations are sometimes required in the evaluation of unclear breast masses. ...
Prediction of function shift in protein families
(2006-08-14)
With the availability of a large number of complete genome sequences, it has become essential to annotate the protein sequences derived from them as precisely as possible. Even though presently available computational ...
Studies on the mechanism of regulation of bile acid synthesis in humans with some aspects on genetic factors
(2005-10-28)
In the present investigation we studied human bile acid synthesis and its regulation both in vivo and in vitro and also evaluated a possible influence of polymorphisms in the CYP7A1 and CYP8B1 genes on bile acid synthesis in vivo. The following...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...
Patellar tendinopathy : on evaluation methods and rehabilitation techniques
(2006-10-27)
Background: Patellar tendinopathy is an increasingly common overuse and degenerative injury for recreational and elite athletes. The management of this injury is often difficult and frustrating and the treatment may take ...
Physical fitness and overweight in Swedish youths
(2005-03-22)
obese. The total prevalence accordingly being 20.1% (95% CI: 18.3% to 22.0%). This sample proved to be heterogeneous concerning overweight status. When obesity and overweight were combined the highest prevalence (26.6%, 95% CI: 21.2 to 32.7) was found...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...