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Langerhans cell histiocytosis : detection, monitoring and pathophysiology
(2002-04-26)
Langerhans cell histiocytosis (LCH) is a rare disease that may occur at any age but mainly affects children. Clonally expanded Langerhans cells together with lymphocytes, eosinophils and macrophages form destructive ...
Implantable devices in heart failure : studies on biventricular pacing and continuous hemodynamic monitoring
(2002-09-13)
trends showed significant (>20%) pressure changes in 9/12 cases of volume overload exacerbation requiring in-hospital treatment. These changes occurred 4±2 days prior to the clinical event. Hospitalizations decreased when the hemodynamic information...
Comparison of stereotactic fine needle aspiration biopsy and core needle biopsy in breast lesions
(2004-04-16)
the 1970th core needle biopsy (CNB) was developed and the method has later been refined. When we started our study 1993, CNB was not used in breast lesions in Sweden.
Biopsy technique: Spinal needles with diameter 0.7 and 0.9 mm were used for S...
Studies on immunological mechanisms of induced arthritis in the rat
(2002-11-22)
pathogenic
and could transfer disease to irradiated recipients.
DNA sequences containing CpG motifs are common in bacteria but rare in
humans. This immunostimulatory DNA induces an innate immune response
through interaction with Tolllike receptor (TLR)-9...
Attention-deficit/hyperactivity disorder : alterations of motor behaviour and dopaminergic transmission
(2004-05-14)
Altered catecholaminergic neurotransmission in the brain has long been
thought to be of importance in the regulation of motor behavior and
cognitive performance in children who had symptoms of distractability,
impulsivity ...
Exposures in utero and chronic disease : an alternative methodological approach
(2002-08-30)
The aims of this thesis were to evaluate maternal and birth characteristics as risk factors for breast cancer and cardiovascular disease later in life, and to assess maternal serum concentrations of insulin-like growth ...
Natural and induced immunity against the tumour-associated antigen, Ep-CAM
(2003-11-27)
The tumour-associated antigen (TAA), Ep-CAM is overexpressed on various human carcinomas, including colorectal carcinoma (CRC). TAAs or their immunodominant epitopes that are spontaneously recognised by the immune system ...
Estrogen receptor b in the urogenital tract of both male and female
(2002-05-24)
The central finding of this thesis is that estrogen receptors regulate androgen receptor expression: ERalpha unpregulates AR and ERbeta down-regulates AR. With this theme, we explored the physiological role of an ER-AR ...
The role of periodontitis in cardiovascular disease
(2004-01-30)
Periodontitis and cardiovascular disease (CVD) are both common diseases affecting a large part of the society. Both diseases are considered to have a chronic inflammatory origin. During the last decades research has focused ...
Tuberculosis and HIV interaction in Ethiopian children : aspects on epidemiology, diagnosis and clinical management
(2002-08-30)
the controls (AOR 12.7; 95% Cl 2.9,55).
The second study explores possible background features associated with
dual infection. These were young age, high educational level of mothers,
having lost one or both parents and being BCG vaccinated. The findings...