Search
Now showing items 1-10 of 28
On the pro-apoptotic mechanisms of the antitumor drugs doxorubicin and interferon-alpha
(2003-11-07)
Anti-cancer drugs act primarily by inducing apoptosis. However, knowledge of how various substances induce apoptosis is still incomplete, and so is the basis for the great variation in cellular sensitivity to cytotoxic ...
Studies of presenilin function in neurodegeneration and in human embryonic CNS during development
(2004-05-21)
markers, after induced
differentiation. Cells began to migrate out of neurospheres after 2 h.
Migrating cells were IR for both PS1 and Notch1 and the neural marker
beta-tubulin III. Cells with features of astrocytes appeared after 8-24 h
but only within...
Nasal airway nitric oxide : methodological aspects and influence of inflammation
(2004-04-02)
Nitric oxide (NO) is an endogenously formed free radical gas involved in numerous biological processes. In 1991 NO was discovered to be present in exhaled air of humans. Soon after, it was reported that the largest amounts ...
Molecular genetic aspects of renal cell carcinoma development
(2003-04-25)
constituted of a deletion of 3p in conventional RCC, and a ring chromosome derived from chromosome 8 in a papillary RCC. Gain of copy number were revealed on chromosomes 3, 5, 7, 8q, and 20, while the losses encompassed 3p and 17p. The SKY and CGH data suggest...
Molecular and diagnostic aspects of the protein p41 of HHV-6 and silencing of the CD46 receptor by RNA interference
(2003-05-23)
Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (CNS), leading to sensory and motor disability in young adults. There is no efficient treatment of the disease. Its etiology is ...
Diagnostic evaluation of fetal death with special reference to intrauterine infections
(2002-05-10)
-99 according to an extensive investigational protocol. A presumptive explanation of the stillbirth was established in 91% of the cases. The most common factors associated with intrauterine fetal death could be identified as infections (24%), placental...
The human placenta : an angiographic study
(2003-04-25)
The arterial vessels from the umbilical cord spreading over the chorion and its cotyledonary branches constitute the main body of the placental vascular tree. In the present study it was visualized by angiography and related ...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...
Studies on human polyomavirus infection in immunosuppressed patients with polyoma related tumors
(2001-09-21)
Polyomaviruses are potentially oncogenic viruses, found in humans, in other mammals and in birds all over the world. The polyomaviruses that have been observed in humans are BK virus (BKV) and JC virus (JCV) as well as the ...
Morbidity in Ménières disease : aspects on quality of life and triggering factors
(2002-11-22)
Menieres disease is an inner ear disorder of unclear origin, characterized by severe attacks of simultaneously appearing fluctuant hearing loss, vertigo, tinnitus and a feeling of aural fullness. The disease has a well-known ...