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Violence in psychiatric inpatient care
(2004-03-05)
This thesis investigates incidents of violence in two psychosis wards, analyses types of violence and the staff's emotional reaction to violence, assesses a new pharmacological treatment strategy of acutely disturbed ...
Functional features of human cytochrome P450 1A2 : with special focus on caffeine and melatonin metabolism
(2002-11-15)
CYP1A2 is one of the major cytochrome P450 enzymes in the liver and metabolises drugs such as caffeine, clozapine, tacrine, and theophylline. CYP1A2 also has a role in chemical carcinogenesis due to its activation of ...
Activation of human dendritic cells : role of the allergenic yeast Malassezia and NK cells
(2002-11-22)
Immature bone marrow derived dendritic cells (DCs) patrol the periphery of our body, where they encounter and take up foreign antigens. Once activated, DCs migrate to regional lymph nodes to present peptides derived from ...
Studies in sporadic inclusion body myositis
(2003-05-15)
Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate ...
Mortality and cancer incidence following cerebral angiography with thorotrast
(2002-08-30)
Epidemiological studies are important tools in assessing radiation-related health effects in humans. The most common form of radiation exposure is low-dose alpha-radiation such as that from radon. However, the long-term ...
Effect of pharmacological treatment of serotonergic function in depression
(2002-05-03)
Since its identification in raphe neurons of the central nervous system (CNS), the biogenic amine serotonin (5- hydroxytryptamin, 5-HT) has been implicated in the etiology and pathophysiology of affective disorders, such as depression. It has been...
The face of wrath : how facial emotion captures visual attention
(2003-05-23)
We look at the things that matter to us. We may rest our eyes on things that attract us, stare at something horrifying, or glare at someone we dislike: things that affect us emotionally are also things that capture our ...
Targeting HIV-1 entry and reverse transcription by vaccination
(2002-11-13)
Human immunodeficiency virus type I (HIV-1) is a complex retrovirus,
which uses the CD4 receptor and chemokine receptors to infect its target
cells. The chemokine receptor CCR5 is essential for primary HIV-1
infection. The hallmark of retroviruses...
Retinoids in experimental neuroblastoma therapy
(2003-01-24)
Retinoids are analogues of vitamin A, with documented activity against various malignant cell types. Neuroblastoma is a childhood tumour of the sympathetic nervous system that shows a complex clinical and biological ...
The role of ethnic identity in care of elderly Finnish immigrants
(2004-01-30)
The role of ethnicity in care of elderly Finnish immigrants Most Western countries are becoming increasingly multicultural because of immigration. Many of these immigrants grow old in a second homeland and will need health ...