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Bronchoalveolar lavage and serum protein patterns in healthy individuals and sarcoidosis patients : a proteomics approach
(2004-01-23)
The etiology of sarcoidosis remains unknown. Although biochemical changes
are frequently observed in sarcoidosis, the problem of finding distinct
biomarkers remains. Only a few markers are defined in this disease. ...
The rhomboid family of intramembrane proteases, conserved regulators of cell communication
(2004-05-14)
The development of multicellular organisms relies heavily on cell
communication. Cells send and receive complex sets of signals,
harmonising their growth and differentiation with that of other, often
distant, cell ...
Pharmacogenetics of human cytochrome P450 3A (CYP3A) enzymes
(2003-10-24)
The cytochrome P450 3A (CYP3A) subfamily encompasses the most important CYP enzymes with respect to drug metabolism, in particular CYP3A4. responsible for the metabolism of a majority of drugs being metabolized in order ...
The human placenta : an angiographic study
(2003-04-25)
The arterial vessels from the umbilical cord spreading over the chorion and its cotyledonary branches constitute the main body of the placental vascular tree. In the present study it was visualized by angiography and related ...
The importance of Escherichia coli fimbriae in urinary tract infection
(2001-11-16)
Urinary tract infection (UTI) is a major bacterial infectious disease among women. Uropathogenic Escherichia coli is the most dominant causative agent. Clinical observations indicate that repeated cystitis induces a ...
Tissue destruction in arthritis : experimental studies
(2003-11-14)
Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. The sensitivity of radiographic ...
Adaptation to ischemia with special emphasis on nitric oxide
(2001-08-31)
Nitric oxide (NO) may play an essential role for maintenance of cardiac function and perfusion. Endothelial dysfunction of atherosclerotic vessels may aggravate cardiac ischemia/reperfusion injury. Adaptation to ischemia ...
Indoor environment and recurrent wheezing in young children
(2003-02-21)
/concrete slab foundation, compared with those living in buildings erected before 1940, OR 2.5 (1.3-4.8) and OR 2.5 (1.1-5.4). This was not primarily explained by differences in type of ventilation systems, measured ventilation rate, occurrence of house dust mite...
Genetic dynamics of HIV-1 : recombination, drug resistance and intrahost evolution
(2004-05-14)
A striking characteristic of HIV is the enormous capacity of genetic
variation. Frequent mutations, deletions, insertions and recombination
events create a population of genetically related but non-identical
viruses ...
Perinatal HIV-1 infection : aspects on clinical presentation, viral dynamics and epidemiology
(2004-09-15)
During the last 20 years HIV-1 infection has changed from being an
unknown disease to being a widespread pandemic, in some areas affecting a
large proportion of the human population. Mother-to-child transmission
(MTCT) ...