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Expression and regulation of vasoactive substances, sex steroids and their receptors in placenta during normal pregnancy and preeclampsia
(2002-04-12)
Despite intense studies preeclampsia remains enigmatic and a major cause of maternal and fetal morbidity and mortality. It is now widely accepted that the placenta has a central role in preeclampsia; delivery of the placenta ...
Blood saving in orthopaedic surgery
(2002-05-10)
509 (316) m] compared to 775 (316) m] in tile supine group (p<0.001).Total blood loss was also lower 1273 (458) ml in the lateral group vs. 1472 (407) mI in the Supine (p<0.05). Reduced hydrostatic blood pressure in the wound and hence reduced bleeding...
Posterior ocular malformations in children : teratological aspects
(2003-05-16)
Posterior ocular malformations are common causes of visual impairment in Swedish children. The most frequent diagnoses within this group are optic nerve hypoplasia and optic nerve/chorioretinal coloboma. Genetic factors, ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
quinazolines, a type of heterocyclic compounds that is considered to be highly interesting as scaffolds for development of new drugs. When the acyl halide was a tertiary 2-haloacyl halide, the reaction instead gave 1,4-benzodiazepine-3-ones via rearrangement...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Effects of gravity and posture on the human lung
(2004-03-18)
subjects in whom acute lung insufficiency was induced by hypergravity. When exposing healthy subjects to 5 times normal gravity (5 G) in the human centrifuge, the arterial oxygen saturation was 84.6 + 1.2% (mean ± SEM) in the supine and 89.7 ± 1.4...
The importance of Escherichia coli fimbriae in urinary tract infection
(2001-11-16)
Urinary tract infection (UTI) is a major bacterial infectious disease among women. Uropathogenic Escherichia coli is the most dominant causative agent. Clinical observations indicate that repeated cystitis induces a ...
Nano-electrospray mass spectrometry for the analysis of neurosteroids and related molecules
(2003-03-10)
converted into their oximes which were detected as protonated molecules with 20 times higher sensitivity than the underivatised steroids. The detection limits for the oximes of 3-oxo-delta4, 20-oxo and 17-oxo steroids were 2.5, 5, and 25 pg/µL, respectively...
Studies on autoimmune diabetes in Latvians and other populations
(2001-10-09)
alleles. IDDM is positively associated with HLA DR3 and DR4 in Caucasians. From HLA-DQ molecules, DQ8 (DQA1*0301- DQB1*0302) is the most prevalent IDDM haplotype in Caucasians, followed by DQ2 (DQA1*0201-DQB1*0501). Taken together, DQ8, DQ2 or both account...
Morbidity in Ménières disease : aspects on quality of life and triggering factors
(2002-11-22)
or vestibular neurectomy) was most beneficial to patients with Menieres disease; 2. To evaluate health-related quality of life issues from a general and disease specific perspective; 3. To find if stress can trigger attacks of Menieres disease; and 4. To propose...