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Functional genomics at the interface of protein expression and biophysical analysis
(2004-02-18)
Protein characterization is central to any functional genomics effort, hence protein expression and purification play fundamental roles in these initiatives. In this study strategies for protein expression in E. coli were ...
Genetic and experimental studies of seasonal affective disorder and related phenotypes
(2003-03-14)
Seasonal affective disorder (SAD) is a subtype of recurrent depressive or bipolar disorder, in which episodes reoccur and remit during a particular season each year. A genetic component in vulnerability to winter SAD has ...
Factors affecting attendance at population-based mammography screening
(2002-01-11)
of disease at diagnosis was obtained from Regional Cancer Registers. Follow-up through 1998 in the Swedish Cause of Death Register revealed that 772 of the 4,645 women had died of breast cancer. Five-year survival was 59% higher among women of higher...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Genetic studies of hypospadias
(2002-11-22)
with low birth weight in 2138 families with at least one boy with hypospadias. There was a familial rate of 7% and a significant lower birth weight in cases with hypospadias compared with their respective brothers, used as controls (p=5x10-13). An increased...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
Molecular monitoring of acute graft-versus-host disease after allogenic stem cell transplantation
(2004-08-20)
Acute graft-versus-host disease (GVHD) remains a major barrier to the wider application of allogeneic stem cell transplantation (SCT) for a variety of diseases. GVHD occurs when the transplanted donor Tlymphocytes react ...
On age related changes in axons and glia of the central nervous system
(2002-08-09)
A growing body of evidence shows that phenotypic changes including axon aberrations, rather than loss of neurons, account for behavioral impairments during aging. The present thesis was undertaken to investigate the ...
Studies on antioxidant and lipid lowering effects on human microcirculation
(2002-10-18)
, microvascular reactivity was found to be markedly
reduced. Treatment for 2 weeks with a daily dose of 1g x 3 of vitamin C
did not significantly improve the vascular reactivity. A slight effect
could however be demonstrated in capillary blood flow velocity...