Search
Now showing items 1-10 of 473
Individualized leukapheresis of hematopoietic cells for cellular therapies
(2005-11-24)
in peripheral blood and HSC collections is by their expression of the CD34-antigen. The optimal dose of HSC for transplantation is today considered to be >5x 106 CD34+ cells /kg bodyweight for prompt hematological recovery of all three lineages whereas a dose...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Functional studies of the multiple endocrine neoplasia type 1 gene
(2004-10-22)
The multiple endocrine neoplasia type 1 (MEN1, OMIM 131 100) syndrome is
an autosomal dominant trait with a near 100% penetrance and with an
estimated prevalence of 2-20/100 000. The syndrome is characterized by
neoplasia ...
Dietary supplements : trends, demographics and mortality among users
(2004-11-05)
Dietary supplements have received growing attention in society and sales
numbers indicate increased use. Still, time trends in prevalence of users
have been unknown. In order to accurately explore associations between
diet ...
Urinary leakage and physical activity in young women
(2005-11-18)
The effect of recreational physical activity on urinary leakage/ incontinence (UL/UI) with regard to load on the pelvic floor (PF) in young women has not been studied specifically.
The aim of the present work was, ...
Biophysical studies on aggregation processes and amyloid fibrils with focus on Alzheimer's disease
(2004-08-13)
Alzheimer's disease (AD) is a fatal neurodegenerative disease, and is the most common form of dementia, affecting 1-2% of the population in industrialized countries. It is believed that intermediate species formed during ...
Studies on the mechanism of regulation of bile acid synthesis in humans with some aspects on genetic factors
(2005-10-28)
In the present investigation we studied human bile acid synthesis and its regulation both in vivo and in vitro and also evaluated a possible influence of polymorphisms in the CYP7A1 and CYP8B1 genes on bile acid synthesis in vivo. The following...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
This thesis is mainly focussed oil the synthesis of marine indole alkaloids and related systems, many of which display interesting biological activities.
In the first part of this thesis we could establish and confirm ...
Bad breath : prevalence, periodontal disease, microflora and inflammatory markers
(2005-03-29)
)] and 841 woman [mean age = 35.7 years (±2.9 SD)] who participated in an epidemiological study of periodontal health that was started in 1985, 2.4 % were found to exhibit foetor ex ore and 1 % were diagnosed as having halitophobia. Subjects with both...
Ribavirin : dose and concentration in treatment of chronic hepatitis C infected patients
(2005-04-29)
viral response was achieved more often in patients with ribavirin concentration above the median concentration of 8.7µM, than below the median. Data are suggesting that higher ribavirin concentrations may lead to better treatment response in genotype 1...