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Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate
(2001-11-15)
work was to characterize dispersed DRG neurons in
culture, a putative model of axotomy, by (1) monitoring Gal and NPY and
their transcripts, (2) investigating the effects of neurotrophic factors
on peptide expression, Glu release and calcium levels and...
Nitric oxide : a marker for inflammation in the lower urinary tract
(2004-05-07)
The main aim of this work is to investigate the role of Nitric oxide (NO)
as a diagnostic marker for inflammation in the lower urinary tract. NO
exerts multiple modulating effects on inflammation and plays a key role
in ...
Differential expression pattern of CEACAM1 isoforms in polarized epithelial cells : it's regulation and some functional consequences
(2004-01-16)
, which increases tyrosine phosphorylation, and
staurosporine, which decreases serine phosphorylation, caused
disappearance of CEACAM1-L from the lateral cell surfaces. By double
staining for adaptor proteins AP-1 and AP-2 as well as for markers for
early...
Biological correlates of HIV-1 heterosexual transmission
(2003-11-24)
HIV-1 infection is a sexually transmitted disease but HIV transmission efficiency by sexual contacts appears to be highly variable; this is probably due to the influence that several behavioural, clinical and biological ...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6...
Minimally invasive hernia surgery
(2003-04-25)
/inflammations, including intestinal obstruction, 58.99. The RR was 2.79 with TAPP and 0.57 with TEP compared to Lichtenstein operated patients....
Studies on HIV-2 antibody mediated neutralisation, coreceptor usage and in vivo tropism
(2001-11-21)
Human immunodeficiency virus type 2 (HIV-2) is the second virus that
causes AIDS in humans. It has a genetic identity with HIV-1 of 40-60% and
similar genetic organisation and biological properties, but the two
viruses are distinguished certain...
Local recurrence after breast conserving surgery in breast cancer
(2002-08-30)
. Generally, the risk of local recurrence was higher than expected, but the estimated survival rates were gratifying. The overall risk of local recurrence was 9.2% at five years and 21.1% at ten years, and the breast cancer-specific survival was 93.3% and 85.2...
Clonidine in paediatric anaesthesia : pharmacokinetic and pharmacodynamic aspects
(2002-04-12)
Clonidine is a mixed alpha-2/alpha-1 adrenoceptor agonist. It reduces sympathetic and increases parasympathetic tone which results in a lowering of the baseline blood pressure and heart rate. Descending posjunctional noradrenergic antinociceptive...
Vestibular control of body orientation in lamprey
(2004-03-26)
Maintenance of body orientation (postural control) is a vital motor function of the brain. The general goal of this project was to understand the organization and operation of neuronal networks responsible for postural ...