Search
Now showing items 1-10 of 55
Characterization and expression of subtypes of nicotinic receptors in brain and adrenal medulla : with focus on development, Alzheimer's disease and transgenic animal models
(2003-08-22)
The cholinergic nicotinic receptors (nAChRs) seem to play an important role in numerous important physiological processes in brain as well as peripheral tissues of man. In first trimester human brain mRNA levels for the alpha3, alpha4, alpha5, alpha...
Invasion promoting factors in endometriotic and endometrial tissue
(2004-05-14)
Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde ...
The diagnostic performance of prostate-specific antigen (PSA) in early detection of prostate cancer : considerations of sensitivity, specificity, lead-time and survival
(2003-09-19)
PSA "cut-off 'value of < 18% improved the diagnostic sensitivity among men with normal PSA levels (i.e., < 3.0 ng/ml), whereas a "cut-off" of 22% increased the specificity at slightly elevated PSA levels (3.0-9.9 ng/mL). In men without PC the %fPSA ratios...
The biological mechanisms in neutrophil and eosinophil adhesion and transmigration in vitro and theur relation to the inflammatory process in vivo
(2001-12-28)
In inflammatory reactions, eosinophils and neutrophils constitute the
major classes of granulocytes that emigrate from the bloodstream into the
tissues. The recruitment of inflammatory cells constitutes a multi-step
process ...
Bile in the oesophagus contributes to the development and complications of gastro-oesophageal reflux disease
(2002-05-10)
Objective: To clarify the relationship between duodenogastro- oesophageal reflux (DGOR) and gastro- oesophageal reflux disease (GORD) and its complications.
Methods: As persons who have had their gallbladders removed ...
Strategies of gene and immune therapy for tumors and viral diseases
(2003-04-04)
In the treatment of tumors and viral diseases such as HIV-1 infection, immunotherapeutic strategies do not seem to have enough capacity to eradicate an already established disease. However, these strategies could play a ...
Tissue destruction in arthritis : experimental studies
(2003-11-14)
Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. The sensitivity of radiographic ...
The transcription machinery in schizosaccharomyces pombe and its regulation
(2004-04-28)
The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the general transcription machinery. The Mediator was originally identified in Saccharomyces cerevisiae ...
Malignant melanoma in children and adolescents
(2003-05-07)
factor may reduce the induction time. For this reason, diagnosis is set at a median age of 55 in adults compared to 15 in adolescents. Median survival time was three years after diagnosis, 15.3% of patients dying as a result of the diagnosed condition...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...