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Work and health : epidemiological studies of sickness absence and mortality with special reference to work environment, factors outside work and unemployment
(2002-02-15)
The level and costs of sickness absence in Sweden have fluctuated over
time and there are also important regional variations within the country
with a higher rate of sickness absence in the northern part. Sickness
absence ...
Studies of genetic and environmental influences on Parkinson’s disease
(2004-01-30)
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. Little is known about the etiology of PD. Although several PD genes are known, these are thought to be involved in ...
Circulating immune complexes in atherosclerotic vascular disease
(2001-08-31)
in those without CICs. Among men
homozygous for C4 null alleles, those who developed MI had higher
concentrations of CICs than did those who remained healthy.
In a five-year prospective study, CICs and antibodies against oxLDL were
associated...
A multidisciplinary system identification of the human precision grip
(2003-11-14)
This thesis focus on the unique human ability to pick up and manipulate small objects using the precision grip, i.e., the fine grip between the index finger and the thumb. This ability is formed by the interplay between ...
Drug treatment in children with focus on off-label drug use
(2010-08-06)
There is a lack of paediatric documentation concerning efficacy and
safety of many drugs, which contribute to drug use outside the terms of the product license (off-label). In the present thesis, four studies (I-IV), using ...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
Hepatitis C in chronic kidney disease and kidney transplantation : with special reference to epidemiology and treatment
(2003-10-31)
Hepatitis C (HCV) is a clinical problem in infected kidney transplant patients but is also a cause of renal disease and vasculitis. Standard therapy for HCV is a combination of interferon and ribavirin. Renal patients have ...
Factors affecting attendance at population-based mammography screening
(2002-01-11)
the mammography register in Uppsala, the Census of 1990 and the Fertility Register (Paper IV). Multivariate analyses among 4,198 non-attenders and 38,972 attenders confirmed that non-attendance was more common among women living without a partner, and among those...
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
generates reactive aldehydes that modify proteins. Two important aldehydes are malondialdehyde (MDA) and 4-hydroxynonenal, which can form covalent adducts on proteins. To analyze the mechanisms for the activation of T cells by aldehyde-modified proteins...
Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'
(2001-11-27)
The aim of elimination test (Et) is to identify tumor antagonizing genes
from chromosome regions that are regularly deleted in microcell hybrid
(MCH) derived tumors through serial SCID mice passages. Et so far was
focused ...