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Population health and inequalities in health : measurement of health-related quality of life and changes in QALYs over time in Sweden
(2003-03-07)
were available (Paper III).
Life expectancy for newborn males (females) increased by 3.68 (2.70) years from 1980/81 to 1996/97 (Paper IV). Expected QALYs increased by 2.64 (0.54). Older persons experienced considerable health gains over time whereas...
Esophageal cancer : evaluation of some new strategies
(2002-03-15)
-chemistry analysis of prechemoradiation biopsies from patients with squamous cell carcinoma of the esophagus regarding the expression of factor VIII, CD-34, p53and bcl-2 and DNA ploidy was described. The results were correlated to tumor response. A method to register...
Supra-threshold hearing loss and wide dynamic range compression
(2004-05-21)
Cochlear hearing loss leads to deficits in many perceptual aspects,
including threshold elevation (loss of sensitivity), reduction of
auditory dynamic range (loudness recruitment) and problems with resolving
sounds (loss ...
Developmentally supportive neonatal care : a study of the newborn individualized developmental care and assessment program (NIDCAP) in a Swedish environment
(2003-04-04)
A family-centred, developmentally supportive approach to newborn intensive care, referred to as the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) has attracted considerable interest in recent ...
Modulation of activity of the tumour suppressor p53 by small molecules and damaged DNA
(2004-04-16)
radiation, p53 rapidly re-localizes to DNA damage sites that also contain gammaH2AX and MRE11 complex. Furthermore, we showed that LSP16-positive p53 is localized in a close vicinity to DNA strand breaks independently of phosphorylation by P13 kinases...
Severe hypoxemia during apnea in humans : influence of cardiovascular responses
(2002-09-13)
When a diving human holds his or her breath, the heart beat slows and the blood vessels constrict in large portions of the body. In diving mammals such as seals, similar responses effectively conserve oxygen for the brain, ...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Mesothelial differentiation, mesothelioma and tumor markers in serous cavities
(2003-05-23)
Mesothelial cells covering the serous membranes are of mesodermal origin although they acquire several characteristics of epithelial cells. The cytological and histological diagnosis of malignant tumors in serous cavities ...
Development of a new PNA analogue as a potential antisense drug and tool for life-science studies
(2004-05-13)
The work described in this thesis focuses on applying synthetic organic chemistry methods (supported by modem synthesizers and analytical techniques) for the preparation of peptides and modified nucleic acids in order to ...
Functional characterization of the alternative reading frame protein p14ARF
(2004-05-06)
in most malignant human tumors. Most intriguingly, both p53 and Rb proteins are in part regulated through the CDKN2A (INK4a/ARF) locus on human chromosome 9p21, a region frequently lost in tumors. This region encodes two structurally and functionally...