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Estrogen receptor signalling in mammary epithelial cells
(2004-05-21)
The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and ...
Cutaneous malignant melanoma aspects of prognostic factors and time : trends in a Swedish population
(2002-11-01)
One of the aims of this thesis was to assess the possible impact of primary and secondary preventive activities in the population of Stockholm-Gotland with the objective to reduce the incidence and mortality from cutaneous ...
Social differences in injury risk in childhood and youth : exploring the roles of structural and triggering factors
(2003-03-21)
Injuries are a leading cause of mortality and morbidity among children and adolescents. Injury risks are not randomly distributed across social groups. The primary aim of this thesis is to increase knowledge about the ...
Clinical, histopathologic and genetic diagnosis in osteogenesis imperfecta and dentinogenesis imperfecta
(2004-01-23)
The aims of this thesis were to investigate (1) dental aberrations in a large sample of unrelated patients with different types and forms of OI, (2) degree of dentin dysplasia in relation to type and form of OI and clinical, ...
Long-term outcome of renal transplantation in childhood
(2003-01-31)
The aim of this thesis was to evaluate the long-term results of renal transplantation in children at Huddinge University Hospital, with special reference to outcome. We therefore evaluated the course of events in children ...
G1-phase cyclin expression in neoplastic B cells
(2002-08-16)
. Our studies suggest that cyclin E protein levels reflect the malignant status of B-ALL blasts, and implicate the potential use of cyclin E as a prognostic marker in adult B-ALL. We also found cyclin E protein overexpression in B-CLL (4/12) and IC (4...
Risk factors for the development of chronic renal failure : epidemiological studies on the role of analgesic use, occupational exposures and socioeconomic background
(2003-01-17)
Chronic renal failure is a severe condition that reduces life expectancy and typically progresses to end-stage renal disease and a need for renal replacement therapy. In a large proportion of cases, chronic renal failure ...
Pain following spinal cord injury
(2004-10-01)
followed up 3 years later regarding the use of analgesic drugs (III) and non-pharmacological treatment (IV). They were also assessed regarding quality of sleep together with a sample of 107 patients with SCI (V). Of 456 patients with an SCI (I), 291 (63.7...
Monitoring and prevention of ischaemia-reperfusion injury in liver transplantation : experimental and clinical studies
(2003-11-07)
Liver function after transplantation is determined not only by the quality of the donor organ or recipient related factors, but also by factors associated with organ preservation. During preservation, the liver graft is ...
Regulation of cytokine receptors and activity markers in eosinophilic inflammatory processes
(2002-05-16)
The eosinophil is an important effector cell in allergic inflammation and asthma and an increased number of eosinophils and eosinophil-derived cytotoxic proteins have been found in blood and airways of allergic patients. ...