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Atrial fibrillation : clinical managements with special emphasis on cardioversion
(2002-08-23)
to 360 J. There were no differences in efficacy, sinus rhythm being obtained in 87 and 91 % in the two groups respectively. One single shock of 360 J caused less chest discomfort than the strategy based on incremental energy shocks. Neither of the two...
Molecular mechanisms of local anaesthetic action on voltage-gated ion channels
(2004-04-02)
In this thesis I try to clarify some molecular mechanisms of local anaesthetic action on ion channels. The traditional view is that local anaesthetics eliminate action potentials by a direct block of Na channels. Other ...
Drug metabolic capacity in Koreans : CYP2D6 & CYP2C19 pheno- and genotype relationships in healthy volunteers and in patients
(2002-05-24)
studied in patients with acid related diseases after repeated doses.
One hundred and fifty-two healthy Korean volunteers were phenotyped with debrisoquine and the metabolic ratio (MR) varied between 0.09 and 6.3, and all were thus extensive metabolizers...
A reason to be bitter : cassava classification from the farmers' perspective
(2001-11-16)
of bitter
taste of the root tip was a good predictor of cyanogenic glucoside levels
(r = 0.65). Mean cyanogenic glucoside level in 132 roots from "cool"
cultivars was 29 mg HCN eq kg-1 fresh weight (Cl 25-33, range 1 - 123),
and in 360 roots from "bitter...
Nephrotic syndrome in children : functional, morphological and therapeutical aspects
(2003-03-21)
or age matched. The glomerular volumes in DMP and FSGS were significantly larger than in those with MCNS(P<0.005, P <0.002). We also found direct correlation between glomerular volume and GFR and ERPF in all patients. In conclusion these results show...
Long-wave ultraviolet radiation (UVA1) and visible light : therapeutic and adverse effects in human skin
(2001-09-05)
the 585 nm fluence were applied with 600 nm,
the lightening was equal to that of 585 nm.
We compared the FPDL at 0.45 msec pulse duration and spot size 5 mm with
an argonpumped dye laser with a robotized scanning laser handpiece
(Hexascan) at 70...
Growth factors in spermatogenesis
(2003-05-16)
The aim of this study was to increase the knowledge of die effects of locally produced growth factors and hormones on germ cell proliferation in rat testis in vitro. Since impaired sperm production and function accounts ...
Determination of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials
(2004-05-17)
We have previously developed a laboratory method that may screen the
Overall Haemostasis Potential (OHP) in plasma based on spectophotometric
measurement of an area under the fibrin aggregation curve in citrated
plasma ...
On the role of cytochrome P450 3A4 in the metabolism of cholesterol and bile acids
(2003-12-19)
The origin of 4beta-hydroxycholesterol, a major oxysterol in human circulation, has previously been unknown. In this thesis, the formation and elimination of this compound are investigated by various techniques. The ...
Masseter muscle pain and its relation to pain mediators in fibromyalgia and local myalgia
(2001-11-09)
The aim of this investigation was to study chronic jaw muscle pain in fibromyalgia, local myalgia and healthy individuals in relation to the pain mediators PGE2, LTB4 and NPY and to study the effects of glucocorticoid ...