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Imaging vision : functional mapping of intermediate visual processes in man
(2001-11-15)
are processed by spatially overlapping mechanisms in early
visual areas, but that illusory contour perception is associated with
stronger activation of a region of ventral extrastriate cortex anterior
to V2. This area has been implicated in the processing...
Insulin resistance in pancreatic cancer
(2003-05-16)
) 2 and 3 mRNA and protein content were determined in other muscle biopsies. Patients with benign gastrointestinal diseases, chronic pancreatitis, and cancer of other sites were investigated as controls. GLUT4 transfected myoblasts were treated...
The kinetic mechanism of microsomal glutathione transferase 1 (MGST1)
(2003-05-16)
various chemical treatments. Reaction of a unique cysteine-49 with sulfhydryl reagents increases the rate of catalysis, up to 30-fold, towards reactive second substrates such as 1-chloro-2,4-dinitrobenzene (CDNB). It is possible that activation, which may...
Body site of cutaneous malignant melanoma : primary tumor location in relation to phenotypic and prognostic factors
(2002-11-08)
The main purpose of this thesis was to analyze the primary body site of cutaneous malignant melanoma (CMM) in relation to phenotypic traits and prognosis. It is clear that several characteristics of CMM are different, and ...
Helicobacter pylori : cellular interactions and pathogenesis
(2001-11-16)
)
production of specific receptors (Leb and NetiAcalpha2,3Galbeta1,4
glycans) and presence or absence of gastric acid; (ii) bacterial
genotype; and (iii) presence or absence of a microflora competing with H.
pylori colonization. The host factors were studied...
Molecular studies of acute myeloid leukemia and the telomerase reverse transcriptase gene
(2002-08-30)
Multiple chromosome rearrangements (MCRs) are detected in approximately 10% of patients with acute myeloid leukemia (AML), and are associated with an adverse prognosis. Comprehensive analysis of the chromosome rearrangements ...
Malignant mesothelioma : an experimental study with emphasis on proteoglycans in mesothelial cell growth and differentiation
(2002-04-17)
) on this process, a series of PGs were analyzed by semi quantitative reversed transcriptase polymerase chain reaction. The cells with epithelial phenotype showed increased expression of syndecan-2, syndecan-4 and hyaluronan synthase, and fibroblast-like cells...
Neuropeptides and spinal antinociception : studies on galanin, nociceptin and endomorphin
(2003-05-29)
, the receptor mediating the effect morphine. Intrathecal (i.t.) application of endomorphin-1 and -2 produced a dose-dependent short lasting depression of the spinal nociceptive flexor reflex in normal rats with comparable potency. The inhibitory effect...
Studies on autoimmune diabetes in Latvians and other populations
(2001-10-09)
IDDM is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting B- cells. GAD65 and IA-2 are major B-cell specific autoantibodies and are not found in healthy population. IDDM is associated with certain HLA class II...
Hepatitis C virus kinetics during antiviral treatment
(2004-03-05)
induction therapy, in combination with ribavirin during treatment of naive patients, also resulted in a small but significantly more pronounced HCV RNA decline compared to standard dosing, in genotype non-1 infected patients but only day 2 and 7 during...