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Cognitive mechanisms in pain processing : assessed with functional imaging methods
(2002-08-09)
The intensity and unpleasantness of a painful experience is often described as correlating well with the degree of noxious stimulation. However, the perception of pain is not a linear phenomenon, reflecting the signal from ...
Stroke severity and outcome : in search of predictors using a population-based strategy
(2002-11-01)
bias on the frequency of different
stroke characteristics; 3) to establish the incidence of neglect and
anosognosia and their impact on disability; 4) to show the impact of
pre-stroke risk factors on stroke severity and case fatality; and 5) to
show...
The effect of sex hormones on hemostasis and cardiovascular riskfactors in postmenopausal women
(2004-10-29)
VII antigen (VIIag) levels of 25 %. Low levels of high density
lipoprotein (HDL) and years since menopause explained an 8% increase in
von Willebrand factor antigen (vWFag) levels. BMI explained 20% and TG 3%
of the increase in plasminogen activator...
On the role of HMGB1 and IL-1 in tissue barrier defense
(2001-11-30)
as the main production sites of the HMGB 1. Surface secretions of the adenoid contained antimicrobial activity mainly consisting of alpha-defensins 1-3.
HMGB1 was found to interact with IL-1 in an IL-1 responsive thymocyte proliferation bioassay and also...
DNA-dependent protein kinase in normal and malignant cells : with special reference to anti-tumour agent sensitivity
(2003-01-03)
The DNA-dependent protein kinase (DNA-PK) is a DNA double strand break (DSB) repair enzyme, essential for the cellular response to DNA damaging agents. DNA-PK is also of importance for lymphoid development, since it includes ...
Imaging studies of cell physiology with particular reference to Na,K-ATPase function
(2003-02-28)
The membrane protein Na,K-ATPase is well known for its critical function of transporting sodium out of the cell and potassium into the cell, thereby creating a fundamental electrochemical gradient upon which several other ...
Mechanisms influencing activation and survival of normal and malignant lymphoid cells in the testis
(2002-11-28)
Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy and the testis is the third most common site of relapse after treatment. Testicular function is regulated by pituitary hormones, but the testicular ...
The GDNF-receptor GFR-alpha-1 : neural expression patterns and regulation in stroke
(2002-03-04)
Background: Neurotrophic factors in the mammalian nervous system are
important for development and survival of neurons and for maintenance and
plasticity of synaptic connections. Additionally, they have been shown ...
Supra-threshold hearing loss and wide dynamic range compression
(2004-05-21)
Cochlear hearing loss leads to deficits in many perceptual aspects,
including threshold elevation (loss of sensitivity), reduction of
auditory dynamic range (loudness recruitment) and problems with resolving
sounds (loss ...
Nephrotic syndrome in children : functional, morphological and therapeutical aspects
(2003-03-21)
Although cure rates of the idiopathic nephrotic syndrome in children have improved because of advances in immunosuppressive therapy, the pathogenesis and course of the disease remain controversial. We have followed children ...