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Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis
(2004-02-06)
novel PDGF family members, PDGF-C and PDGF-D in tumor growth and tumor angiogenesis.
Characterization of the expression pattern of two isoforms of VEGF-B, VEGF-B167 and VEGF-B186 in tissues and cell lines indicate that VEGF-B167 is the predominant...
Dendritic cell and IgA responses in SIV and HIV-1 pathogenesis
(2004-04-28)
Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV-1) can infect different subsets of dendritic cells (DC). Such cells may therefore not only be involved in the generation of recruitment of naïve T and B lymphocytes...
Optimisation in strategies in diffusion tensor MR imaging
(2002-04-12)
strategies to improve the image quality and reliability of the DTI data and diffusion anisotropy maps are presented. These include simulation studies to determine 1) which anisotropy index is most insensitive to noise and 2) which diffusion scheme (i.e. which...
Assessment of physical activity and energy expenditure in adolescents
(2002-04-15)
were that: 1) there was no significant difference for the data on TEE and time spent at PA of moderate intensity or higher between the HR monitoring method and the activity diary; 2) the fitness level of the subjects affected the use of absolute HR when...
Molecular and diagnostic aspects of the protein p41 of HHV-6 and silencing of the CD46 receptor by RNA interference
(2003-05-23)
Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (CNS), leading to sensory and motor disability in young adults. There is no efficient treatment of the disease. Its etiology is ...
Experienced physical functioning and effects of resistance training in patients with chronic kidney disease
(2004-04-15)
Physical fitness declines as chronic kidney disease progresses, and is approximately 50% of the expected norm when starting dialysis therapy This means that physical fitness in these patients is so reduced that it impinge ...
Drug use in the elderly : risk or protection? Findings from the Kungsholmen project
(2004-02-27)
status.
Study IV: Use of glucocorticoids was associated with a significantly
higher risk of dementia in carriers of the apoE epsilon4 allele (RR 2.39,
95% CI 1.02-5.58).
Study V: Use of calcium channel blockers did not protect against AD...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
quinazolines, a type of heterocyclic compounds that is considered to be highly interesting as scaffolds for development of new drugs. When the acyl halide was a tertiary 2-haloacyl halide, the reaction instead gave 1,4-benzodiazepine-3-ones via rearrangement...
Genetic dynamics of HIV-1 : recombination, drug resistance and intrahost evolution
(2004-05-14)
A striking characteristic of HIV is the enormous capacity of genetic
variation. Frequent mutations, deletions, insertions and recombination
events create a population of genetically related but non-identical
viruses ...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...