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Management of Helicobacter pylori infection in Vietnam
(2004-05-07)
.1 % were still H. pylori positive and 58.7% were free from peptic ulcer after one year. ELISA based on Vietnamese antigens showed a specificity of 96.4% and sensitivity of 91.0% compared to 96.4% and 69.4%, respectively, when Swedish antigens were used...
Matrix degrading proteases in vascular disease
(2002-11-22)
polymorphisms within the promoter regions of MMP-7 and MMP-12. In the MMP-7 promoter we found two polymorphisms located at -181 with an A to G substitution and the other one at -153 with a C to T substitution. Both of the MMP-7 polymorphisms were associated...
Sarcoidosis : inflammatory mechanisms and markers of activity
(2002-10-25)
Sarcoidosis is a disease characterized by an accumulation of CD4+ T-lymphocytes in affected organs. Previous findings of an association between the HLA-allele DR17 and an accumulation in bronchoalveolar lavage fluid (BALF) ...
Skin cancer prevention : readiness to change sun-related behaviours
(2004-04-02)
The general aim of this thesis was to collect data relevant for skin
cancer prevention and to investigate the applicability of the
Transtheoretical Model for sun-related behaviour. Also, to assess the
readiness to change ...
Assignment and assessment of orthology and gene function
(2004-01-30)
Several genomes from different species have been sequenced over the last years, most notably the human genome. An important task of computational biology is to classify and functionally annotate the large amount of sequence ...
Trinucleotide repeats and neuropsychiatric phenotypes
(2001-11-02)
between affected offspring and healthy family members was seen. Two loci, ERDA1 on chromosome 17 and CTG18.1 on chromosome 18 were analyzed by PCR in the families. Eighty-nine percent of the RED expansions correlated in size with large alleles at these two...
Genetic factors influencing susceptibility to intracellular infections
(2002-05-15)
Genetics of susceptibility to infection is a complex trait in which many factors from the host, the parasite and the environment, interact to produce different clinical manifestations of disease.
This thesis explores ...
Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity
(2003-01-24)
grafts. The 5-year probability of survival was 52 % for MUD vs. 77% for sibling recipients (p= 0.014). In ALL, the survival of the MUD (77%) and sibling group was equal. In SAA, survival was 43% vs. 86% (p=0.09) and in metabolic disorders 63% vs. 89% (p=0...
Studies of polyglutamine repeats and their biology in relation to disease
(2001-08-23)
reported. In paper 111, 41 affected individuals from five French
and one Polish FSP families linked to SPG4 were tested for expanded
CAG/CTG repeats using the RED method, PCR for the ERDA1 and CTG18.1 loci
as well as by Western blot for expressed...
Risk factors for the development of chronic renal failure : epidemiological studies on the role of analgesic use, occupational exposures and socioeconomic background
(2003-01-17)
to that among never-exposed (odds ratio, 1.01; 95% Cl, 0.81-1.25). No dose-response relationships were observed for lifetime cumulative solvent exposure, average dose, or exposure frequency or duration. The absence of association pertained to all subgroups...