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Aspects of care among HIV infected patients : needs, adherence to treatment and health related quality of life
(2002-09-06)
The HIV disease has many manifestations, some of which may compromise the patient's well- being and quality of life. In addition, the intake of antiretroviral drugs entails inconvenience or discomfort that may degrade the ...
Coagulation and inflammation in experimental endotoxemia in vitro and in vivo : monitoring method and effects of nicotinamide
(2003-03-07)
In gram negative sepsis, endotoxin from the bacterial membrane elicits proinflammatory and procoagulant host responses. Sepsis and its frequent complication disseminated intravascular coagulation (DIC) are leading causes ...
Molecular changes in the tumour suppressor genes p53 and CDKN2A/ARF in human urinary bladder cancer
(2002-01-25)
Urinary bladder neoplasm is the ninth most common cancer in Europe and the United States. The incidence in Sweden is approximately 32 for men and 9 for women per 105 subjects and year and almost all cases are transitional cell carcinoma (TCC). Many...
Case-crossover studies of the triggering of disease : myocardial infarction and Ménières disease
(2003-05-07)
premonitory symptoms and ongoing vigorous exertion was 6.1 (95% Cl: 4.3-9.0). Beyond 45 minutes after the end of exertion no increased risk was found. Effect modification was found from physical fitness, where the risk among sedentary patients was 54.7 (95% CI...
Does cancer originate in utero?
(2002-02-22)
The purpose of the present thesis was to evaluate Trichopoulos' hypothesis that breast cancer can originate in utero, and to examine the role of antenatal estrogen exposure in the etiology of testicular cancer.
First, ...
Structure-function studies of GDNF and other members of the TGF-beta superfamily
(2002-10-22)
recruited to the complex, becoming
autophosphorylated on several cytoplasmic tyrosine residues.
Phosphotyrosine residues on active Ret form a platform for the
recruitment of multiple adaptor and effector proteins. There are two main
isoforms of Ret, Ret9...
Noradrenergic augmentation strategies in the pharmacological treatment of depression and schizophrenia : an experimental study
(2002-08-23)
The pharmacological treatment of depression and schizophrenia, two major psychiatric disorders, is largely based on modulation of central monoaminergic neurotransmission. However, currently available pharmacological treatment ...
Improving the situation of urinary bladder cancer survivors treated with radical surgery or radical radiotherapy
(2002-10-18)
. A 9-fold increased risk for defecation urgency and an 11-fold increased risk for faecal leakage was reported by the irradiated patients as compared to the matched controls (II). The risk of being affected by these symptoms was also increased...
Mortality and cancer incidence following cerebral angiography with thorotrast
(2002-08-30)
Epidemiological studies are important tools in assessing radiation-related health effects in humans. The most common form of radiation exposure is low-dose alpha-radiation such as that from radon. However, the long-term ...
Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice
(2004-01-09)
Obesity is a major health problem because of its dramatic increase in
prevalence and its association with type 2 diabetes, coronary heart
diseases, hypertension and stroke. It is well known that signals
generated in ...