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Molecular epidemiology of human papillomavirus and cervical cancer
(2001-11-16)
), clustering of different STI was commonly
absent.
Presence of antibodies to HPV did not predict survival among cervical
cancer patients (OR 0,64; CI 95 % 0,4-1,1). In Latvia, the most important
risk factor for cervical cancer was presence of cervical HPV 16...
Using SNPs to study complex genetic disease : a population and evolutionary genetics perspective
(2004-05-21)
Associating genes to complex genetic diseases has proven more difficult
than anticipated. Many genetic variants contribute small effects towards
an individual's disease predisposition in polygenic diseases, and ...
Supra-threshold hearing loss and wide dynamic range compression
(2004-05-21)
Cochlear hearing loss leads to deficits in many perceptual aspects,
including threshold elevation (loss of sensitivity), reduction of
auditory dynamic range (loudness recruitment) and problems with resolving
sounds (loss ...
Growth factor pathways in human cancer : functional and therapeutic implications
(2002-10-04)
The multi-step development of tumors involves numerous changes at genomic level such as oncogene activation, loss of function of tumor suppressor genes and translocations resulting in fusion genes that encodes for chimeric ...
Decoding NK cell receptor specificity : functional and structural studies of MHC class 1 subcomponents
(2002-08-30)
Natural Killer (NK) cells are an important part of the innate immune system. They can lyse target cells and secrete immunoregulatory cytokines early during immune responses. They mediate protection against viruses and ...
Appetitive and consummatory ingestive behavior : role of taste, dopamine and NPY
(2001-11-23)
The present thesis has examined the role of taste, dopamine and
neuropeptide Y (NPY) in the regulation of the two phases of ingestive
behavior: appetitive (approaching and handling of food) and consummatory
ingestive ...
Lower limb ischemia in women
(2004-02-27)
Arteriosclerosis is a general disease affecting different parts of the arterial system. In coronary heart disease (CHD) women have different risk factors, symptoms, indication for treatment, interpretation of diagnostic ...
Method development for analysis of 8-oxodG as a biomarker for oxidative stress
(2001-11-22)
Oxidative damage to DNA gives oxidation of DNA bases and strand breaks
that can cause mutations leading to cancer. Various forms of agents are
capable of oxidising DNA in vivo including peroxides, singlet oxygen and
UV- ...
On prognostic and treatment predictive factors in early stage breast cancer
(2002-05-03)
Breast cancer is the most common malignant tumor in Swedish women and the incidence is increasing with 1-2% per year in the Stockholm area. A subgroup of patients is women diagnosed with primary inoperable disease. This ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...