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Cardiovascular function after long-term bed rest
(2001-08-31)
On earth, daily activities involve standing, changes of posture and various types of muscle action, all of which challenge the cardiovascular regulation. Removal of the orthostatic stress for a longer period, as during ...
Developmental and stress induced changes in peptide and catecholamine content of the paraaortic paraganglia
(2000-05-05)
. The reduction of ENK-LI was strikingly parallel to the reduction of the CAs and was significant at all times between 1.5 and 4 hours after insulin administration (20 U/kg). Reserpine (15 mg/kg) reduced the CA content in both the PAB and adrenal glands three...
Tonsillar cancer : incidence, prevalence of HPV and survival
(2008-04-04)
Since human papilloma virus (HPV) in the mid 1980ies was first observed
in squamous cell carcinoma of the head and neck, its role and impact,
especially on oral and oropharyngeal cancer, have attracted extensive
interest. ...
Role of p70 S6 kinase in the formation of tau pathologies in Alzheimer’s disease
(2005-08-10)
found that 100 PM zinc could induce an increase of p-p70S6K, pPKB, p-GSK-3beta, p-ERK1/2, p-JNK, and p-p38, especially in long-term treatment (4 to 8h) in serum-deprived SH-SY5Y cells. Treatment with different inhibitors including rapamycin, wortmannin...
Evaluation of strategies to predict and improve early graft survival in clinical islet transplantation
(2010-05-21)
Transplantation of the islets of Langerhans as a treatment for type 1
diabetes (T1DM) is a procedure still under development. For the last
decade it has been possible to obtain insulin independence by repeated
infusions ...
Regulation of Plasmodium falciparum virulence genes and immune response to surface antigens in placental malaria
(2011-11-15)
Malaria infection caused by the parasite Plasmodium falciparum is a deadly torment, especially for young children and pregnant women residing in sub-Saharan Africa. Much of the parasites virulence is due to its ability to ...
Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting
(2013-11-07)
Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration ...