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Characterisation of chromosomal aberrations in childhood leukaemia
(2001-05-16)
Acute lymphoblastic leukaemia (ALL) is the most common malignancy in childhood, accounting for approximately 25% of all paediatric malignancies. Based on clinical risk criteria and modem laboratory investigations including ...
Moderately preterm infants : studies on length of hospital stay and neonatal outcome
(2011-05-03)
Objective: Moderately preterm infants account for a large proportion of admissions and bed-days in neonatal units. Determinants of length of hospital stay, contemporary measures of morbidity by gestational week and risk ...
Renal cell death in urinary tract infections : role of E. coli toxins
(2005-01-28)
Febrile urinary tract infections (UTI) are common bacterial illnesses in children. Several follow up studies have shown that 10-15 % of infants with pyelonephritis will develop permanent renal damage, i.e., renal scars, ...
A novel drug and device in anesthesia : with focus on breathing and upper airway physiology
(2018-04-12)
Anesthesia-related airway complications are associated with hypoxia due to inability to secure or maintain the airway with subsequent insufficient ventilation and gas exchange. This thesis has explored the impact on airway ...
Long-term outcome after hypothermia-treated hypoxic-ischaemic encephalopathy
(2022-05-13)
Hypoxic-ischaemic encephalopathy (HIE) is a major cause of acquired brain injury in newborn infants. It is a potentially life-threatening condition that leaves survivors at substantial risk of life-long debilitating sequelae ...
Cell cycle and differentiation in Giardia Lamblia
(2008-04-30)
Giardia lamblia is the major cause of waterborne diarrhea worldwide.
Giardiasis is initiated by ingestion of cysts, which after passing
through the stomach are triggered to excyst. Excystation, or awakening
from dormancy, ...
Hormonal regulation of HES-1 in breast cancer cells
(2008-05-21)
Hairy and Enhancer of Split homolog 1 (HES-1) is a transcriptional repressor belonging to the basic helix-loop-helix family of proteins, and has been shown to have a pivotal role as a regulator of neurogenesis, myogenesis ...
Immunological alterations, therapies with immune check-point inhibitors and beyond in patients with metastatic melanoma
(2020-10-07)
In the last decade the treatment of metastatic melanoma (MM) has been revolutionized and changed the life of many patients, offering prolonged survival and improved symptom control. These treatment strategies have also ...
Signalling pathways controlling bacterial adaptation
(2009-03-27)
The conversion of environmental signals into cellular responses is a critically important process that occurs in all organisms. The ability to process information depends, in general, on complex signal transduction and ...
The information-seeking behaviors of professionals and information sources in the field of injury prevention and safety promotion
(2008-09-23)
Injuries are a serious public health problem worldwide. Despite the
ubiquity of the World Wide Web and the resources of many different
literature databases, the search for information concerning Injury
Prevention and ...