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Factors affecting peri-implant tissue reactions
(2001-04-27)
Screw- shaped titanium implants are today routinely used m the substitution of lost teeth. In this thesis some of the biological factors related to the long-term survival and maintenance of dental implants were studied.
The ...
Epstein-Barr virus and genomic instability : a new look at the mechanisms of viral oncogenesis
(2010-12-20)
EBV is associated with a variety of lymphoid and epithelial malignancies but the mechanisms of oncogenesis are still not fully understood. The aim of the work described in this thesis was to assess whether induction of ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
. The third-degree perineal injuries alone were reduced from 14.0% to 10.9% (-3.1, 95% CI -3.7 to -2.4) with NNT 32. The fourth-degree perineal injuries alone were reduced from 1.6% to 1.0 % (-0.6%, 95% CI -0.8 to -0.4). Fourth-degree perineal injuries...
Intravenous access in distressed children : effects of midazolam and nitrous oxide on success rate, hormone and metabolic stress responses
(2011-04-29)
Background and Aims: Intravenous (IV) access has demonstrated high levels of pain and distress in children. A stress full IV access should be avoided, primarily by the children, but also for the parents and staff. When ...
von Willebrand disease in women : heavy menstrual bleeding and obstetrical bleeding
(2018-09-25)
Von Willebrand disease is the most common inherited bleeding disorder worldwide with a prevalence, reaching 1% of general population. vWD is equally distributed between genders. However, vWD-affected females experience ...
Assays for monitoring HIV therapy in low-middle income countries
(2013-05-20)
associated mutations (RAMs) according to direct sequencing. Additional resistance mutations corresponding to <20% of the viral populations were found by UDPS in 9 analysed patients. In four of these, the mutations are likely to have contributed to phenotypic...
Balance control in older adults with Parkinson’s disease : effects of medication and exercise
(2015-12-23)
Aim: To investigate the effects of dopaminergic medications on turning while walking in
older adults with mild to moderate Parkinson’s disease (PD). A further aim was to develop a
training program targeting balance ...
Dysregulated Notch signaling in breast cancer and liver disease
(2015-10-13)
The evolutionarily conserved Notch signaling pathway regulates crucial aspects of development and tissue homeostasis. This thesis contributes research towards understanding a role of non-canonical Notch signaling in the ...
Genetic aspects of HIV-1 evolution and transmission
(2008-05-02)
HIV-1 is one of the fastest evolving organisms known to man. Its rate of evolution is approximately one million times faster than that of higher organisms such as ourselves, meaning that the amount of changes within the ...
Characterization of HIV-1 populations in infected cells
(2013-03-21)
Human immunodeficiency virus (HIV) is one of the most fatal diseases in the world today, and the most important worldwide infectious disease in terms of mortality. This virus infects and kills cells of the immune system ...