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Re-establishing reading skills of elderly low vision patients : studies on Swedish low vision clinic clients
(2000-11-17)
This thesis is based on the project "Reading skills, reading training and technology for the visually handicapped - Prospects for the 1990s," carried out at the Department of Educational Research of the Stockholm Institute ...
Re-establishing reading skills of elderly low vision patients : studies on Swedish low vision clinic clients
(2013-02-13)
This thesis is based on the project "Reading skills, reading training and technology for the visually handicapped - Prospects for the 1990s," carried out at the Department of Educational Research of the Stockholm Institute ...
Unraveling genetic mechanisms in autism spectrum disorders
(2011-09-08)
cases, while heart defects, short neck and/or redundant skin folds, eye abnormalities, and ear anomalies were present in the majority of cases. By our finding we could narrow down the critical region for the 6p22 deletion phenotype to 2.2 Mb comprising...
Effects of chemotherapy on bone growth and chondrocyte cell death signaling
(2010-11-01)
. Therefore, we hypothesized that Bax, a pro-apoptotic member of the Bcl-2 family that is known to regulate intrinsic apoptosis, may play a key role in dexamethasone-induced retardation of bone growth. In chondrocytes, dexamethasone induced conformational...
Every bug counts : neonatal colonization and infection of Gram-negative bacilli : aspects on antibiotic resistance in Sweden and Ecuador
(2020-09-18)
Neonatal infections caused by extended-spectrum beta-lactamase (ESBL)-producing Gramnegative bacilli are associated with high morbidity and mortality. In order to perform targeted preventive interventions against the impacts ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
significantly higher rate of intrapartum cesarean section among women ≥40 years, both after spontaneous onset of labor (adjusted odds ratio (aOR) 3.07, 95%CI 2.81-3.35) and induction of labor (aOR 2.51, 95%CI 2.24-2.81). The risk of VE was also increased...
Functional assays for the diagnosis of primary defects in lymphocyte cytotoxicity
(2015-11-02)
was not clear. In Paper V, we studied NK cell cytotoxicity using ORAI1 and STIM1-deficient patients, confirming abrogated Ca2+ entry upon target cell stimulation. Importantly, ORAI1 and STIM1-deficient NK cells did not degranulate nor produced proinflammatory...
EBV membrane protein LMP2A interactions with ubiquitin ligases and a signaling scaffold
(2004-09-24)
interactions with the host cell will therefore contribute both to a better understanding of cellular signaling pathways, the regulation of EBV latency and to treatment of EBV-associated malignancies. Years of LMP2A research lead to the conclusion that LMP2A...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
% confidence interval (CI): 20.9–24.8] or 0.32 USD. Monthly income, occupation, geographic location and educational level were the main determinants of WTP. Study III suggested that the insured of CBHI were 2.111 (95% CI: 1.458- 3.079) times more likely than...
RNA polymerase I inhibition : mechanism and exploitation in cancer treatment
(2022-10-10)
with underappreciated RiBi-inhibitory effects for cancer treatment; 2. the effects of Pol I inhibition in high-grade gliomas (HGG) and identify synergistic treatment strategies to prevent potential resistance development; and 3. alternative druggable Ri...