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Violence towards health care personnel : prevalence, risk factors, prevention and relation to quality of care
(1998-11-18)
This thesis investigates the prevalence and nature of violence towards health care personnel and its implications for quality of care. The research presented here is based on a comprehensive perspective of violence as an ...
Pulmonary surfactant proteins B and C : molecular organisation and involvement in respiratory disease
(2000-11-23)
Lung surfactant is a complex mixture of phospholipids and proteins with the main function to reduce the surface tension at the alveolar air/liquid interface. Surfactant protein B (SP-B) and C (SP-C) are hydrophobic but ...
Expression and function of TRP channels in peripheral sensory neurons
(2009-05-19)
and adult stages. Cellular localisation studies of selected channels in the DRG further revealed expression in different neuronal subtypes. TRPC1 and TRPC2 were primarily found in large sized mechanosensitive neurons, TRPC3 was exclusively found in non...
Psychiatric comorbidity in multiple sclerosis : biological and epidemiological aspects
(2017-01-23)
Multiple sclerosis (MS) is a chronic, neuroinflammatory disease and one of the leading reasons for neurological disability among young people in the Western World. MS patients commonly experience neuropsychiatric symptoms ...
Adhesion molecules and synapse remodeling during motoneuron regeneration
(2009-10-09)
the expression of nectin-3-binding necl-5. Nectin proteins did not localize to synapses on spinal motoneurons, but instead to neuronal processes and glia, both within the spinal cord and in the lesioned sciatic nerve. Immunoreactivity for N-cadherin localized...
Effects of acute exercise and training on gene expression and regulatory proteins in human skeletal muscle
(2019-05-20)
Regular physical activity affects all tissues in the human body, not least skeletal muscle. The skeletal muscle adaptation involves changes that help the muscle to handle perturbations of the intracellular homeostasis ...
Coagulation during and after cardiopulmonary bypass with focus on heparin, protamine, aprotinin and platelet function
(2019-05-10)
Background: Heparin and protamine dosing for anticoagulation during cardiopulmonary bypass (CPB) and its reversal after CPB, respectively, is usually given according to body weight. Excess protamine may impair coagulation. ...
The red blood cell as a mediator of vascular dysfunction in type 2 diabetes and COVID-19
(2021-11-03)
Background: The number of patients diagnosed with Type 2 Diabetes (T2D) is steadily increasing and accounts for a large proportion of cardiovascular complications. Endothelial dysfunction represents an early disturbance ...
Proteolysis of insulin-like growth factor-binding protein-1, -2 and -4 : function of fragments
(2011-12-21)
The insulin-like growth factors (IGF-I and IGF-II) stimulate cell growth, survival and differentiation, and have insulin-like activity. A family of six IGF-binding proteins (IGFBP-1 through -6) bind to IGFs with high ...
Exercise-induced molecular mechanisms in untrained and life-long highly trained individuals
(2020-08-21)
Regular physical activity results in extensive systemic and functional adaptation effects in the human body that contribute to physical performance, such as muscular strength and endurance, and can have beneficial health ...