Search
Now showing items 1-10 of 11
Dynamics of oncogenic human papillomavirus infection
(2000-10-06)
Background: Sexually transmitted oncogenic human papillomaviruses(HPVs), particularly HPV type 16, are the major cause of several human cancers, notably cervical and other anogenital cancers. The spread of these infections ...
Renal dysfunction and protection in cardiovascular surgery
(2000-09-15)
Purpose: This thesis is focused on studies of postoperative renal dysfunction (PRD), and on renal effects and possible prophylactic potentials of three vasoactive substances, calcitonin gene-related peptide (CGRP), atrial ...
Insights from comorbidity into multiple sclerosis aetiology and outcomes
(2014-10-31)
Aim: The overall aim of this research was to investigate the nature of the comorbidities in multiple sclerosis (MS) in four large population-based studies. The first study assessed whether the diagnosis underlying ...
Radiomics in cancer prognosis : applications and limitations of quantitative texture analysis
(2018-11-16)
Medical imaging has become an integral part of clinical diagnostics since the discovery of X-rays at the end of the 19th century. Recent advances in computing power have opened up the possibility to extract quantitative ...
Musculoskeletal injuries and generalized joint laxity in ballet dancers
(2012-09-13)
. In study II, the ballet dancers were found to have a less prominent thoracic kyphosis, lumbar lordosis, and showed a higher incidence of joint mobility. In Study III, the injury incidence was 0.8/1,000 hours of activity and the injury incidence tended...
Reproductive health in adolescent girls with special emphasis on menstrual disorders, bone health, sexuality and social factors
(2009-05-11)
Menstrual disturbances are common during adolescence, especially within the first 1-3 years after menarche, and are often explained by immaturity of the hypothalamic-pituitary-gonadal axis. However, little is known about ...
E-epidemiology : adapting epidemiological methods for the 21st century
(2009-08-28)
The traditional methods in epidemiological data collection are both costly and time consuming and less convenient for longitudinal large-scale studies. During the last decades, epidemiological studies suffer from low ...
Investigating the treatment of metastatic breast cancer : real-world evidence on treatment patterns, safety and efficacy
(2022-05-25)
Metastatic breast cancer is an incurable disease causing a spectrum of symptoms and leading
to a continuous deterioration of performance status and quality of life. It is a heterogeneous
disease, with survival being ...
Genetic determinants of breast cancer risk
(2011-01-19)
The main purpose of this thesis was to identify genetic risk factors using both hypothesis-based and hypothesis-free approaches.
In an attempt to identify common disease susceptibility alleles for breast cancer, we ...
Older people's home modification process
(2008-08-08)
The overall aim of the thesis was to provide theoretical and empirical
knowledge of interactions involved in the encounters between older
persons experiencing activity limitations in their home environments and
the ...