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Isolation and characterization of genes within the region for multiple endocrine neoplasia type 1 on chromosome 11q13
(1996-09-06)
in the 5' direction giving a transcript of 4400 bp and a total open reading frame of 1234 amino acids, the same size as detected by Northern blot analysis. The complete transcription unit of PLCB3 is approximately 15 kb, contains 31 exons, and is preceded...
Pain and radiographic changes of the arthritic temporomandibular joint : relation to cytokines in synovial fluid and plasma
(2000-11-24)
In patients with rheumatoid arthritis and other inflammatory joint diseases, radiographic changes of the TMJ are frequently observed. Common symptoms of TMJ involvement are pain at rest and on movement of the jaw. This ...
Function, expression and polymorphism of human alcohol dehydrogenase 3/glutathionedependent formaldehyde dehydrogenase
(2001-05-02)
Alcohol dehydrogenase 3 (ADH3), identical to glutathione-dependent formaldehyde dehydrogenase, plays a vital role in the defense against formaldehyde through the activity for the spontaneously formed adduct between ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Immediate skin-to-skin contact for very preterm and low birth weight infants : from newborn physiology to mortality reduction
(2022-05-17)
infants, and from one register study. Studies I and II involved very preterm infants in Scandinavia, where study I (n=55) investigated the effect on infant temperature at one postnatal hour and study II (n=91) infant cardiorespiratory parameters during...
Getting going on getting better : how is systematic quality improvement established in a healthcare organization? Implications for change management theory and practice
(2007-08-31)
Despite the widespread application of quality improvement (QI), there is
enduring uncertainty about its effectiveness in healthcare as an approach
to the inevitable, but challenging, task of managing organizational
change. ...
Pharmacological and analytical studies of the cyclin dependent kinase inhibitors
(2009-10-30)
Cyclin-dependent kinases (Cdks) play a key role in the regulation of cell cycle progression and RNA transcription. Deregulation of Cdks has been associated with several malignancies, neurodegenerative disorders, viral and ...
Personality traits among individuals who as adolescents consulted for a substance use problem
(2013-03-15)
Background: Adolescent antisocial behavior including substance misuse is associated with negative consequences both for the individual and the society, for example school drop-out, and high costs in the criminal justice ...